Sulfanilides

Organic compounds that contain a sulfonanilide group; this functional group is a type of sulfonamide consisting of a sulfur atom bonded to two oxygen atoms via double bonds, one carbon atom, and one nitrogen atom; they are derivatives of aniline.

1 – 15 of 38 results

CH5132799, MedChemExpress

MedChemExpress CH5132799 is a selective class I PI3K inhibitor. CH5132799 inhibits class I PI3Ks, particularly PI3Kα, with an IC50 of 14 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	377.42
Color	Gray
Physical Form	Solid
Chemical Name or Material	CH5132799
Grade	Research
SMILES	NC1=NC=C(C2=C3C(N(S(=O)(C)=O)CC3)=NC(N4CCOCC4)=N2)C=N1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.81%
CAS	1007207-67-1
Solubility Information	DMSO : 4.55 mg/mL (12.06 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₉N₇O₃S
Formula Weight	377.42

AZ876, MedChemExpress

MedChemExpress AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	439.57
Color	Orange
Physical Form	Solid
Chemical Name or Material	AZ876
Grade	Research
SMILES	O=C(C(NC1=CC=C(N2CCCCC2)C=C1)=C3C4=CC=CC=C4)N(C(C)(C)C)S3(=O)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.26%
CAS	898800-26-5
Solubility Information	DMSO : 100 mg/mL (227.50 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₉N₃O₃S
Formula Weight	439.57

MK-8033, MedChemExpress

MedChemExpress MK-8033 is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation. MK-8033 can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	471.53
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	MK-8033
Grade	Research
SMILES	O=S(NCC1=CC=CC=N1)(CC2=CC=C3C(C(C4=CC(C5=CN(N=C5)C)=CN=C4C=C3)=O)=C2)=O
For Use With (Application)	Cancer-Kinase/protease
CAS	1001917-37-8
Solubility Information	DMSO : ≥ 46 mg/mL (97.55 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₁N₅O₃S
Formula Weight	471.53

GNE-131, MedChemExpress

MedChemExpress GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	442.57
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GNE-131
Grade	Research
SMILES	O=S(NC1=NN=C2N1C=C(C3CC3)C(OCC45C[C@@H](C6)C[C@@H](C[C@@H]6C5)C4)=C2)(C7CC7)=O
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.97%
CAS	1629063-81-5
Solubility Information	DMSO : 125 mg/mL (282.44 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₃₀N₄O₃S
Formula Weight	442.57

Pifithrin-μ, MedChemExpress

MedChemExpress Pifithrin-μ is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity.

Pricing and Availability

IBR2, MedChemExpress

MedChemExpress IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	400.49
Color	Pink
Physical Form	Solid
Chemical Name or Material	IBR2
Grade	Research
SMILES	O=S(N1C(C2=CNC3=C2C=CC=C3)C4=C(C=CC=C4)C=C1)(CC5=CC=CC=C5)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.6%
CAS	313526-24-8
Solubility Information	DMSO : ≥ 100 mg/mL (249.69 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₀N₂O₂S
Formula Weight	400.49

Methazolamide, MedChemExpress

MedChemExpress Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	236.27
Color	White
Physical Form	Solid
Chemical Name or Material	Methazolamide
Grade	Research
SMILES	CC(/N=C1SC(S(=O)(N)=O)=NN/1C)=O
Percent Purity	99.43%
CAS	554-57-4
Solubility Information	DMSO : ≥ 50 mg/mL (211.62 mM)
Health Hazard 1	H302∣H312∣H332
Synonym	L584601
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula	C₅H₈N₄O₃S₂
Formula Weight	236.27

Selexipag, MedChemExpress

MedChemExpress Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	496.62
Color	White
Physical Form	Solid
Chemical Name or Material	Selexipag
Grade	Research
SMILES	O=C(NS(=O)(C)=O)COCCCCN(C1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)N=C1)C(C)C
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.89%
CAS	475086-01-2
Solubility Information	DMSO : ≥ 50 mg/mL (100.68 mM)
Synonym	NS-304 ACT-293987
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₃₂N₄O₄S
Formula Weight	496.62

ETP-46321, MedChemExpress

MedChemExpress ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2.3 and 14.2 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	473.55
Color	Off-White
Physical Form	Solid
Chemical Name or Material	ETP-46321
Grade	Research
SMILES	NC(N=C1)=NC=C1C2=CN3C=C(CN4CCN(S(=O)(C)=O)CC4)N=C3C(N5CCOCC5)=N2
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.65%
CAS	1252594-99-2
Solubility Information	DMSO : ≥ 33 mg/mL (69.69 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₇N₉O₃S
Formula Weight	473.55

BMS-214662, MedChemExpress

MedChemExpress BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	489.61
Color	White
Physical Form	Solid
Chemical Name or Material	BMS-214662
Grade	Research
SMILES	N#CC1=CC=C(N(CC2=CN=CN2)C[C@@H](CC3=CC=CC=C3)N(S(=O)(C4=CC=CS4)=O)C5)C5=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.59%
CAS	195987-41-8
Solubility Information	DMSO : ≥ 100 mg/mL (204.24 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₃N₅O₂S₂
Formula Weight	489.61

SR3335, MedChemExpress

MedChemExpress SR3335 (ML 176) is a selective RORα inverse agonist that directly binds to RORα with a Ki of 220 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	405.34
Color	Off-White
Physical Form	Solid
Chemical Name or Material	SR3335
Grade	Research
SMILES	O=S(C1=CC=CS1)(NC2=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C2)=O
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	99.43%
CAS	293753-05-6
Solubility Information	DMSO : ≥ 100 mg/mL (246.71 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	ML 176
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₃H₉F₆NO₃S₂
Formula Weight	405.34

Begacestat, MedChemExpress

MedChemExpress Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease.

Pricing and Availability

CZC24832, MedChemExpress

MedChemExpress CZC24832 is a highly selective and potent PI3Kγ inhibitor (IC50=27 nM) with apparent dissociation constants (Kdapp) of 19 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	364.4
Color	Off-White
Physical Form	Solid
Chemical Name or Material	CZC24832
Grade	Research
SMILES	FC1=CC(C2=CC(S(=O)(NC(C)(C)C)=O)=CN=C2)=CN3C1=NC(N)=N3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.35%
CAS	1159824-67-5
Solubility Information	DMSO : ≥ 53 mg/mL (145.44 mM)
Health Hazard 1	H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₇FN₆O₂S
Formula Weight	364.4

TC-G-1008, MedChemExpress

MedChemExpress TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	418.9
Color	White
Physical Form	Solid
Chemical Name or Material	TC-G-1008
Grade	Research
SMILES	CS(=O)(NC1=CC=C(CNC2=NC(NC)=NC(C3=NC=CC=C3)=C2)C(Cl)=C1)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.03%
CAS	1621175-65-2
Solubility Information	DMSO : ≥ 100 mg/mL (238.72 mM)
Synonym	GPR39-C3
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₈H₁₉ClN₆O₂S
Formula Weight	418.9

Litronesib Racemate, MedChemExpress

MedChemExpress Litronesib Racemate (LY2523355 Racemate) is the racemate of litronesib. Litronesib is a selective, allosteric inhibitor of kinesin Eg5.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	511.7
Color	White
Physical Form	Solid
Chemical Name or Material	Litronesib Racemate
Grade	Research
SMILES	CC(C)(C)C(N1C(C2=CC=CC=C2)(CNS(CCNCC)(=O)=O)SC(NC(C(C)(C)C)=O)=N1)=O
Percent Purity	99.2%
CAS	546111-97-1
Solubility Information	DMSO : 100 mg/mL (195.43 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	LY2523355 Racemate
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₃₇N₅O₄S₂
Formula Weight	511.7

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