Sulfanilides

Organic compounds that contain a sulfonanilide group; this functional group is a type of sulfonamide consisting of a sulfur atom bonded to two oxygen atoms via double bonds, one carbon atom, and one nitrogen atom; they are derivatives of aniline.

1 – 15 of 38 results

IBR2, MedChemExpress

MedChemExpress IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	400.49
Color	Pink
Physical Form	Solid
Chemical Name or Material	IBR2
Grade	Research
SMILES	O=S(N1C(C2=CNC3=C2C=CC=C3)C4=C(C=CC=C4)C=C1)(CC5=CC=CC=C5)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.6%
CAS	313526-24-8
Solubility Information	DMSO : ≥ 100 mg/mL (249.69 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₀N₂O₂S
Formula Weight	400.49

Methazolamide, MedChemExpress

MedChemExpress Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	236.27
Color	White
Physical Form	Solid
Chemical Name or Material	Methazolamide
Grade	Research
SMILES	CC(/N=C1SC(S(=O)(N)=O)=NN/1C)=O
Percent Purity	99.43%
CAS	554-57-4
Solubility Information	DMSO : ≥ 50 mg/mL (211.62 mM)
Health Hazard 1	H302∣H312∣H332
Synonym	L584601
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula	C₅H₈N₄O₃S₂
Formula Weight	236.27

GNE-131, MedChemExpress

MedChemExpress GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	442.57
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GNE-131
Grade	Research
SMILES	O=S(NC1=NN=C2N1C=C(C3CC3)C(OCC45C[C@@H](C6)C[C@@H](C[C@@H]6C5)C4)=C2)(C7CC7)=O
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.97%
CAS	1629063-81-5
Solubility Information	DMSO : 125 mg/mL (282.44 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₃₀N₄O₃S
Formula Weight	442.57

Pifithrin-μ, MedChemExpress

MedChemExpress Pifithrin-μ is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity.

Pricing and Availability

AZ876, MedChemExpress

MedChemExpress AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	439.57
Color	Orange
Physical Form	Solid
Chemical Name or Material	AZ876
Grade	Research
SMILES	O=C(C(NC1=CC=C(N2CCCCC2)C=C1)=C3C4=CC=CC=C4)N(C(C)(C)C)S3(=O)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.26%
CAS	898800-26-5
Solubility Information	DMSO : 100 mg/mL (227.50 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₉N₃O₃S
Formula Weight	439.57

MK-8033, MedChemExpress

MedChemExpress MK-8033 is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation. MK-8033 can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	471.53
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	MK-8033
Grade	Research
SMILES	O=S(NCC1=CC=CC=N1)(CC2=CC=C3C(C(C4=CC(C5=CN(N=C5)C)=CN=C4C=C3)=O)=C2)=O
For Use With (Application)	Cancer-Kinase/protease
CAS	1001917-37-8
Solubility Information	DMSO : ≥ 46 mg/mL (97.55 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₁N₅O₃S
Formula Weight	471.53

CH5132799, MedChemExpress

MedChemExpress CH5132799 is a selective class I PI3K inhibitor. CH5132799 inhibits class I PI3Ks, particularly PI3Kα, with an IC50 of 14 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	377.42
Color	Gray
Physical Form	Solid
Chemical Name or Material	CH5132799
Grade	Research
SMILES	NC1=NC=C(C2=C3C(N(S(=O)(C)=O)CC3)=NC(N4CCOCC4)=N2)C=N1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.81%
CAS	1007207-67-1
Solubility Information	DMSO : 4.55 mg/mL (12.06 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₉N₇O₃S
Formula Weight	377.42

CZC24832, MedChemExpress

MedChemExpress CZC24832 is a highly selective and potent PI3Kγ inhibitor (IC50=27 nM) with apparent dissociation constants (Kdapp) of 19 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	364.4
Color	Off-White
Physical Form	Solid
Chemical Name or Material	CZC24832
Grade	Research
SMILES	FC1=CC(C2=CC(S(=O)(NC(C)(C)C)=O)=CN=C2)=CN3C1=NC(N)=N3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.35%
CAS	1159824-67-5
Solubility Information	DMSO : ≥ 53 mg/mL (145.44 mM)
Health Hazard 1	H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₇FN₆O₂S
Formula Weight	364.4

Begacestat, MedChemExpress

MedChemExpress Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease.

Pricing and Availability

TC-G-1008, MedChemExpress

MedChemExpress TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	418.9
Color	White
Physical Form	Solid
Chemical Name or Material	TC-G-1008
Grade	Research
SMILES	CS(=O)(NC1=CC=C(CNC2=NC(NC)=NC(C3=NC=CC=C3)=C2)C(Cl)=C1)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.03%
CAS	1621175-65-2
Solubility Information	DMSO : ≥ 100 mg/mL (238.72 mM)
Synonym	GPR39-C3
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₈H₁₉ClN₆O₂S
Formula Weight	418.9

ML335, MedChemExpress

MedChemExpress ML335 is a selective activator of both TREK-1 and TREK-2.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	373.25
Color	White
Physical Form	Solid
Chemical Name or Material	ML335
Grade	Research
SMILES	O=C(NCC1=CC=C(Cl)C=C1Cl)C2=CC=C(NS(=O)(C)=O)C=C2
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.93%
CAS	825658-06-8
Solubility Information	DMSO : 155 mg/mL (415.27 mM; Need ultrasonic and warming)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₄Cl₂N₂O₃S
Formula Weight	373.25

Reparixin, MedChemExpress

MedChemExpress Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	283.39
Color	White
Physical Form	Solid
Chemical Name or Material	Reparixin
Grade	Research
SMILES	CS(=O)(NC([C@@H](C1=CC=C(CC(C)C)C=C1)C)=O)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	95.05%
CAS	266359-83-5
Solubility Information	DMSO : ≥ 100 mg/mL (352.87 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Health Hazard 1	H302
Synonym	Repertaxin DF 1681Y
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₄H₂₁NO₃S
Formula Weight	283.39

GNE-477, MedChemExpress

MedChemExpress GNE-477 is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	504.63
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GNE-477
Grade	Research
SMILES	NC1=NC=C(C2=NC(N3CCOCC3)=C4C(C(C)=C(CN5CCN(S(=O)(C)=O)CC5)S4)=N2)C=N1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.7%
CAS	1032754-81-6
Solubility Information	DMSO : 16.67 mg/mL (33.03 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₈N₈O₃S₂
Formula Weight	504.63

Litronesib, MedChemExpress

MedChemExpress Litronesib (LY2523355) is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	511.7
Color	White
Physical Form	Solid
Chemical Name or Material	Litronesib
Grade	Research
SMILES	CC(C)(C)C(N1[C@@](C2=CC=CC=C2)(CNS(CCNCC)(=O)=O)SC(NC(C(C)(C)C)=O)=N1)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.48%
CAS	910634-41-2
Solubility Information	DMSO : ≥ 50 mg/mL (97.71 mM)
Synonym	LY2523355
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₃₇N₅O₄S₂
Formula Weight	511.7

FGH10019, MedChemExpress

MedChemExpress FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	373.49
Color	Earth Yellow
Physical Form	Solid
Chemical Name or Material	FGH10019
Grade	Research
SMILES	CS(=O)(NC1=CC=C(C2=CSC(C3=CC(CCC)=NC=C3)=N2)C=C1)=O
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	99.43%
CAS	1046045-61-7
Solubility Information	DMSO : ≥ 38 mg/mL (101.74 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₈H₁₉N₃O₂S₂
Formula Weight	373.49

Sulfanilides

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