Benzenesulfonamides

Organic compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an amino group; considered the amide of benzenesulfonic acid.

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1 – 15 of 237 results

Probenecid, 98%

CAS: 57-66-9 Molecular Formula: C13H19NO4S Molecular Weight (g/mol): 285.36 MDL Number: MFCD00038402 InChI Key: DBABZHXKTCFAPX-UHFFFAOYSA-N Synonym: probenecid,4-dipropylsulfamoyl benzoic acid,probenecid acid,probecid,benecid,benemid,benuryl,probalan,probenemid,probexin PubChem CID: 4911 ChEBI: CHEBI:8426 IUPAC Name: 4-(dipropylsulfamoyl)benzoic acid SMILES: CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O

Pricing and Availability
Specifications

PubChem CID	4911
CAS	57-66-9
Molecular Weight (g/mol)	285.36
ChEBI	CHEBI:8426
MDL Number	MFCD00038402
SMILES	CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
Synonym	probenecid,4-dipropylsulfamoyl benzoic acid,probenecid acid,probecid,benecid,benemid,benuryl,probalan,probenemid,probexin
IUPAC Name	4-(dipropylsulfamoyl)benzoic acid
InChI Key	DBABZHXKTCFAPX-UHFFFAOYSA-N
Molecular Formula	C13H19NO4S

Glybenzcyclamide, 99%

CAS: 10238-21-8 Molecular Formula: C23H28ClN3O5S Molecular Weight (g/mol): 494.003 MDL Number: MFCD00056625 InChI Key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N Synonym: glyburide,glibenclamide,glybenclamide,micronase,diabeta,glynase,daonil,euglucon,maninil,semi-daonil PubChem CID: 3488 ChEBI: CHEBI:5441 IUPAC Name: 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

Pricing and Availability
Specifications

PubChem CID	3488
CAS	10238-21-8
Molecular Weight (g/mol)	494.003
ChEBI	CHEBI:5441
MDL Number	MFCD00056625
SMILES	COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Synonym	glyburide,glibenclamide,glybenclamide,micronase,diabeta,glynase,daonil,euglucon,maninil,semi-daonil
IUPAC Name	5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
InChI Key	ZNNLBTZKUZBEKO-UHFFFAOYSA-N
Molecular Formula	C23H28ClN3O5S

S,S-Dimethyl-N-(p-toluenesulfonyl)sulfoximine, 98%

CAS: 22236-45-9 Molecular Formula: C9H13NO3S2 Molecular Weight (g/mol): 247.327 MDL Number: MFCD00013922 InChI Key: IRNAWARRPQUZDU-UHFFFAOYSA-N Synonym: s,s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-p-tolylsulfonyl sulfoximine,dimethyl 4-methylbenzenesulfonyl imino-??-sulfanone,maybridge1_004531,s,s-dimethyl-n-p-tolylsulphonyl sulphoximide,dimethyl n-p-toluenesulfonyl sulfoximine,dimethyl-n-4-toluenesulfonyl sulfoximine,n-para-toluenesulfonyl dimethylsulfoximine,s.s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-4-methylphenylsulfonyl sulfoximide PubChem CID: 99226 IUPAC Name: N-[dimethyl(oxo)-$l^{6}-sulfanylidene]-4-methylbenzenesulfonamide SMILES: CC1=CC=C(C=C1)S(=O)(=O)N=S(=O)(C)C

Pricing and Availability
Specifications

PubChem CID	99226
CAS	22236-45-9
Molecular Weight (g/mol)	247.327
MDL Number	MFCD00013922
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N=S(=O)(C)C
Synonym	s,s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-p-tolylsulfonyl sulfoximine,dimethyl 4-methylbenzenesulfonyl imino-??-sulfanone,maybridge1_004531,s,s-dimethyl-n-p-tolylsulphonyl sulphoximide,dimethyl n-p-toluenesulfonyl sulfoximine,dimethyl-n-4-toluenesulfonyl sulfoximine,n-para-toluenesulfonyl dimethylsulfoximine,s.s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-4-methylphenylsulfonyl sulfoximide
IUPAC Name	N-[dimethyl(oxo)-$l^{6}-sulfanylidene]-4-methylbenzenesulfonamide
InChI Key	IRNAWARRPQUZDU-UHFFFAOYSA-N
Molecular Formula	C9H13NO3S2

Hydrochlorothiazide, MedChemExpress

MedChemExpress Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	297.74
Color	White
Physical Form	Solid
Chemical Name or Material	Hydrochlorothiazide
Grade	Research
SMILES	O=S(C1=C(Cl)C=C(C2=C1)NCNS2(=O)=O)(N)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.49%
CAS	58-93-5
Solubility Information	DMSO : 50 mg/mL (167.93 mM; Need ultrasonic)
Synonym	HCTZ
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₇H₈ClN₃O₄S₂
Formula Weight	297.74

AKR1C3-IN-1, MedChemExpress

MedChemExpress AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	317.36
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	AKR1C3-IN-1
Grade	Research
SMILES	O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O
Percent Purity	98.74%
CAS	327092-81-9
Solubility Information	DMSO : ≥ 100 mg/mL (315.10 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₆H₁₅NO₄S
Formula Weight	317.36

L755507, MedChemExpress

MedChemExpress L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing in CRISPR/Cas9 nickase system.

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Etebenecid, MedChemExpress

MedChemExpress Etebenecid is a uricosuric agents, lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys, also inhibits penicillin tubular secretion.

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Acetohexamide, MedChemExpress

MedChemExpress Acetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	324.4
Color	White
Physical Form	Solid
Chemical Name or Material	Acetohexamide
Grade	Research
SMILES	O=S(C1=CC=C(C(C)=O)C=C1)(NC(NC2CCCCC2)=O)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.39%
CAS	968-81-0
Solubility Information	DMSO : 25 mg/mL (77.07 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₂₀N₂O₄S
Formula Weight	324.4

Alofanib, MedChemExpress

MedChemExpress Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	413.4
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Alofanib
Grade	Research
SMILES	O=C(O)C1=CC=CC(S(=O)(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)=O)=C1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.81%
CAS	1612888-66-0
Solubility Information	DMSO : ≥ 30.1 mg/mL (72.81 mM)
Synonym	RPT835
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₅N₃O₆S
Formula Weight	413.4

HMN-176, MedChemExpress

MedChemExpress HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1), without significant effect on tubulin polymerization.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	382.43
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	HMN-176
Grade	Research
SMILES	O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2/C=C/C3=CC=N(C=C3)=O)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.54%
CAS	173529-10-7
Solubility Information	DMSO : ≥ 30 mg/mL (78.45 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₈N₂O₄S
Formula Weight	382.43

SU11274, MedChemExpress

MedChemExpress SU11274 is a selective Met inhibitor with IC50 of 10 nM, but has no effects on PGDFRβ, EGFR or Tie2.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	568.09
Color	Orange
Physical Form	Solid
Chemical Name or Material	SU11274
Grade	Research
SMILES	O=S(C1=CC2=C(C=C1)NC(/C2=C/C3=C(C(C(N4CCN(CC4)C)=O)=C(N3)C)C)=O)(N(C)C5=CC=CC(Cl)=C5)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.19%
CAS	658084-23-2
Solubility Information	DMSO : ≥ 100 mg/mL (176.03 mM)
Synonym	PKI-SU11274
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₃₀ClN₅O₄S
Formula Weight	568.09

LX2343, MedChemExpress

MedChemExpress LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	474.91
Color	White
Physical Form	Solid
Chemical Name or Material	LX2343
Grade	Research
SMILES	O=C(NC1=CC=C(OCO2)C2=C1)CN(C3=CC(Cl)=CC=C3OC)S(=O)(C4=CC=CC=C4)=O
For Use With (Application)	Neuroscience-Neurodegeneration
Percent Purity	99.74%
CAS	333745-53-2
Solubility Information	DMSO : ≥ 100 mg/mL (210.57 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₁₉ClN₂O₆S
Formula Weight	474.91

TG101209, MedChemExpress

MedChemExpress TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	509.67
Color	Gray
Physical Form	Solid
Chemical Name or Material	TG101209
Grade	Research
SMILES	O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C2C)=C1)(NC(C)(C)C)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.81%
CAS	936091-14-4
Solubility Information	DMSO : ≥ 50 mg/mL (98.10 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₃₅N₇O₂S
Formula Weight	509.67

Sulfamethoxypyridazine, MedChemExpress

MedChemExpress Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic, for treatment of Dermatitis herpetiformis.

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AZD2098, MedChemExpress

MedChemExpress AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	334.18
Color	White
Physical Form	Solid
Chemical Name or Material	AZD2098
Grade	Research
SMILES	O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.86%
CAS	566203-88-1
Solubility Information	DMSO : 100 mg/mL (299.24 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₁H₉Cl₂N₃O₃S
Formula Weight	334.18

Benzenesulfonamides

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