Benzenesulfonamides

Organic compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an amino group; considered the amide of benzenesulfonic acid.

1 – 15 of 237 results

Probenecid, 98%

CAS: 57-66-9 Molecular Formula: C13H19NO4S Molecular Weight (g/mol): 285.36 MDL Number: MFCD00038402 InChI Key: DBABZHXKTCFAPX-UHFFFAOYSA-N Synonym: probenecid,4-dipropylsulfamoyl benzoic acid,probenecid acid,probecid,benecid,benemid,benuryl,probalan,probenemid,probexin PubChem CID: 4911 ChEBI: CHEBI:8426 IUPAC Name: 4-(dipropylsulfamoyl)benzoic acid SMILES: CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O

Pricing and Availability
Specifications

PubChem CID	4911
CAS	57-66-9
Molecular Weight (g/mol)	285.36
ChEBI	CHEBI:8426
MDL Number	MFCD00038402
SMILES	CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
Synonym	probenecid,4-dipropylsulfamoyl benzoic acid,probenecid acid,probecid,benecid,benemid,benuryl,probalan,probenemid,probexin
IUPAC Name	4-(dipropylsulfamoyl)benzoic acid
InChI Key	DBABZHXKTCFAPX-UHFFFAOYSA-N
Molecular Formula	C13H19NO4S

Glybenzcyclamide, 99%

CAS: 10238-21-8 Molecular Formula: C23H28ClN3O5S Molecular Weight (g/mol): 494.003 MDL Number: MFCD00056625 InChI Key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N Synonym: glyburide,glibenclamide,glybenclamide,micronase,diabeta,glynase,daonil,euglucon,maninil,semi-daonil PubChem CID: 3488 ChEBI: CHEBI:5441 IUPAC Name: 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

Pricing and Availability
Specifications

PubChem CID	3488
CAS	10238-21-8
Molecular Weight (g/mol)	494.003
ChEBI	CHEBI:5441
MDL Number	MFCD00056625
SMILES	COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Synonym	glyburide,glibenclamide,glybenclamide,micronase,diabeta,glynase,daonil,euglucon,maninil,semi-daonil
IUPAC Name	5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
InChI Key	ZNNLBTZKUZBEKO-UHFFFAOYSA-N
Molecular Formula	C23H28ClN3O5S

S,S-Dimethyl-N-(p-toluenesulfonyl)sulfoximine, 98%

CAS: 22236-45-9 Molecular Formula: C9H13NO3S2 Molecular Weight (g/mol): 247.327 MDL Number: MFCD00013922 InChI Key: IRNAWARRPQUZDU-UHFFFAOYSA-N Synonym: s,s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-p-tolylsulfonyl sulfoximine,dimethyl 4-methylbenzenesulfonyl imino-??-sulfanone,maybridge1_004531,s,s-dimethyl-n-p-tolylsulphonyl sulphoximide,dimethyl n-p-toluenesulfonyl sulfoximine,dimethyl-n-4-toluenesulfonyl sulfoximine,n-para-toluenesulfonyl dimethylsulfoximine,s.s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-4-methylphenylsulfonyl sulfoximide PubChem CID: 99226 IUPAC Name: N-[dimethyl(oxo)-$l^{6}-sulfanylidene]-4-methylbenzenesulfonamide SMILES: CC1=CC=C(C=C1)S(=O)(=O)N=S(=O)(C)C

Pricing and Availability
Specifications

PubChem CID	99226
CAS	22236-45-9
Molecular Weight (g/mol)	247.327
MDL Number	MFCD00013922
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N=S(=O)(C)C
Synonym	s,s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-p-tolylsulfonyl sulfoximine,dimethyl 4-methylbenzenesulfonyl imino-??-sulfanone,maybridge1_004531,s,s-dimethyl-n-p-tolylsulphonyl sulphoximide,dimethyl n-p-toluenesulfonyl sulfoximine,dimethyl-n-4-toluenesulfonyl sulfoximine,n-para-toluenesulfonyl dimethylsulfoximine,s.s-dimethyl-n-p-toluenesulfonyl sulfoximine,s,s-dimethyl-n-4-methylphenylsulfonyl sulfoximide
IUPAC Name	N-[dimethyl(oxo)-$l^{6}-sulfanylidene]-4-methylbenzenesulfonamide
InChI Key	IRNAWARRPQUZDU-UHFFFAOYSA-N
Molecular Formula	C9H13NO3S2

Hydrochlorothiazide, MedChemExpress

MedChemExpress Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	297.74
Color	White
Physical Form	Solid
Chemical Name or Material	Hydrochlorothiazide
Grade	Research
SMILES	O=S(C1=C(Cl)C=C(C2=C1)NCNS2(=O)=O)(N)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.49%
CAS	58-93-5
Solubility Information	DMSO : 50 mg/mL (167.93 mM; Need ultrasonic)
Synonym	HCTZ
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₇H₈ClN₃O₄S₂
Formula Weight	297.74

AKR1C3-IN-1, MedChemExpress

MedChemExpress AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	317.36
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	AKR1C3-IN-1
Grade	Research
SMILES	O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O
Percent Purity	98.74%
CAS	327092-81-9
Solubility Information	DMSO : ≥ 100 mg/mL (315.10 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₆H₁₅NO₄S
Formula Weight	317.36

NXT629, MedChemExpress

MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	609.78
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	NXT629
Grade	Research
SMILES	O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.2%
CAS	1454925-59-7
Solubility Information	DMSO : 125 mg/mL (204.99 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₅H₃₉N₅O₃S
Formula Weight	609.78

Pazopanib, MedChemExpress

MedChemExpress Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	437.52
Color	White
Physical Form	Solid
Chemical Name or Material	Pazopanib
Grade	Research
SMILES	O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	444731-52-6
Solubility Information	DMSO : 62.5 mg/mL (142.85 mM; Need ultrasonic)
Synonym	GW786034
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₃N₇O₂S
Formula Weight	437.52

Sulfachloropyridazine, MedChemExpress

MedChemExpress Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.

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Sulfacarbamide, MedChemExpress

MedChemExpress Sulfacarbamide is a blood sugar-lowering drug, also acting on the vegetative nervous system.

Pricing and Availability

2-Aminobenzenesulfonamide, MedChemExpress

MedChemExpress 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.

Pricing and Availability

VR23, MedChemExpress

MedChemExpress VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	477.88
Color	Yellow
Physical Form	Solid
Chemical Name or Material	VR23
Grade	Research
SMILES	O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.05%
CAS	1624602-30-7
Solubility Information	DMSO : 33.33 mg/mL (69.75 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₆ClN₅O₆S
Formula Weight	477.88

ISCK03, MedChemExpress

MedChemExpress ISCK03 is a specific SCF/c-Kit inhibitor.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	355.45
Color	Light Yellow
Physical Form	Powder
Chemical Name or Material	ISCK03
Grade	Research
SMILES	O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.27%
CAS	945526-43-2
Solubility Information	DMSO : ≥ 38 mg/mL (106.91 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₂₁N₃O₂S
Formula Weight	355.45

PSB-12062, MedChemExpress

MedChemExpress PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	337.39
Color	White
Physical Form	Solid
Chemical Name or Material	PSB-12062
Grade	Research
SMILES	O=S(N1C2=C(C=CC=C2)OC3=CC=CC=C13)(C4=CC=C(C)C=C4)=O
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.06%
CAS	55476-47-6
Solubility Information	DMSO : 25 mg/mL (74.10 mM; Need ultrasonic)
Health Hazard 1	H302
Synonym	N-(p-Methylphenylsulfonyl)phenoxazine
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₅NO₃S
Formula Weight	337.39

NMS-859, MedChemExpress

MedChemExpress NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	349.79
Color	Gray
Physical Form	Solid
Chemical Name or Material	NMS-859
Grade	Research
SMILES	O=S1(C2=CC=CC=C2C(NC3=CC(NC(CCl)=O)=CC=C3)=N1)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.01%
CAS	1449236-96-7
Solubility Information	DMSO : ≥ 42 mg/mL (120.07 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₅H₁₂ClN₃O₃S
Formula Weight	349.79

Terutroban, MedChemExpress

MedChemExpress Terutroban is a thromboxane-prostaglandin receptor antagonist.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	407.91
Color	White
Physical Form	Solid
Chemical Name or Material	Terutroban
Grade	Research
SMILES	O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	95.0%
CAS	165538-40-9
Solubility Information	DMSO : ≥ 22 mg/mL (53.93 mM)
Synonym	S-18886
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₂ClNO₄S
Formula Weight	407.91

Benzenesulfonamides

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