Pyrroles
Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.
Grade
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Physical Form
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Quantity
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- (106)
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- (38)
- (1)
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- (150)
- (126)
- (8)
Percent Purity
- (20)
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- (1)
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- (4)
- (5)
- (65)
- (9)
- (6)
- (13)
- (6)
- (12)
- (21)
- (3)
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- (5)
- (9)
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- (5)
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- (10)
- (2)
- (8)
- (8)
- (4)
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- (6)
- (4)
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- (2)
- (5)
- (1)
- (6)
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1
PCI-34051, MedChemExpress
MedChemExpress PCI-34051 is a potent and selective HDAC8 inhibitor with IC50 of 10 nM, with >200-fold selectivity over the other HDAC isoforms.
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| Molecular Weight (g/mol) | 296.32 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | PCI-34051 |
| Grade | Research |
| SMILES | COC(C=C1)=CC=C1CN2C3=CC(C(NO)=O)=CC=C3C=C2 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 97.28% |
| CAS | 950762-95-5 |
| Solubility Information | DMSO : ≥ 30 mg/mL (101.24 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C17H16N2O3 |
| Formula Weight | 296.32 |
2
SB269652, MedChemExpress
MedChemExpress SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology.
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3
Apyramide, MedChemExpress
MedChemExpress Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.
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| Molecular Weight (g/mol) | 490.93 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Apyramide |
| Grade | Research |
| SMILES | O=C(OC1=CC=C(NC(C)=O)C=C1)CC2=C(C)N(C(C3=CC=C(Cl)C=C3)=O)C4=C2C=C(OC)C=C4 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.06% |
| CAS | 68483-33-0 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C27H23ClN2O5 |
| Formula Weight | 490.93 |
4
Oncrasin-1, MedChemExpress
MedChemExpress Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells.
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| Molecular Weight (g/mol) | 269.73 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Oncrasin-1 |
| Grade | Research |
| SMILES | O=CC1=CN(CC(C=C2)=CC=C2Cl)C3=CC=CC=C31 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.28% |
| CAS | 75629-57-1 |
| Solubility Information | DMSO : ≥ 43 mg/mL (159.42 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H12ClNO |
| Formula Weight | 269.73 |
5
NVP-AEW541, MedChemExpress
MedChemExpress NVP-AEW541 (AEW541) is a potent inhibitor of IGF-1R with IC50 of 0.15 μM, also inhibits InsR, with IC50 of 0.14 μM.
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| Molecular Weight (g/mol) | 439.55 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | NVP-AEW541 |
| Grade | Research |
| SMILES | NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCC4)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.45% |
| CAS | 475489-16-8 |
| Solubility Information | DMSO : 50 mg/mL (113.75 mM; Need ultrasonic) |
| Synonym | AEW541 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C27H29N5O |
| Formula Weight | 439.55 |
6
LLY-507, MedChemExpress
MedChemExpress LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.
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| Molecular Weight (g/mol) | 574.76 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | LLY-507 |
| Grade | Research |
| SMILES | O=C(C1=CC(C2=CC=CC=C2N3CCN(CCN4C=C(C)C5=C4C=CC=C5)CC3)=CC(C#N)=C1)NCCCN6CCCC6 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.47% |
| CAS | 1793053-37-8 |
| Solubility Information | DMSO : 15 mg/mL (26.10 mM; Need ultrasonic and warming) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C36H42N6O |
| Formula Weight | 574.76 |
7
CMK, MedChemExpress
MedChemExpress CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.
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| Molecular Weight (g/mol) | 358.82 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | CMK |
| Grade | Research |
| SMILES | NC1=C(C2=NC=N1)C(C3=CC=C(C=C3)C)=C(N2CCCO)C(CCl)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.2% |
| CAS | 821794-90-5 |
| Solubility Information | DMSO : 150 mg/mL (418.04 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen) |
| Shelf Life | 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen) |
| Molecular Formula | C18H19ClN4O2 |
| Formula Weight | 358.82 |
8
ALB-127158(a), MedChemExpress
MedChemExpress ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.
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| Molecular Weight (g/mol) | 404.44 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | ALB-127158(a) |
| Grade | Research |
| SMILES | O=C1C=C(OCC2=NC=C(F)C=C2)C=CN1C3=CC4=C(C=C3)C(CNCC5)=C5N4C |
| For Use With (Application) | Metabolism-protein/nucleotide metabolism |
| Percent Purity | 99.6% |
| CAS | 1173154-32-9 |
| Solubility Information | Ethanol : 2 mg/mL (4.95 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C23H21FN4O2 |
| Formula Weight | 404.44 |
9
Optovin, MedChemExpress
MedChemExpress Optovin is a reversible photoactivated TRPA1 ligand that enables light-mediated neuronal excitation. Optovin activates TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues.
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| Molecular Weight (g/mol) | 315.41 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Optovin |
| Grade | Research |
| SMILES | O=C1NC(S/C1=C\C2=C(C)N(C3=CC=CN=C3)C(C)=C2)=S |
| Percent Purity | 96.47% |
| CAS | 348575-88-2 |
| Solubility Information | DMSO : ≥ 37 mg/mL (117.31 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H13N3OS2 |
| Formula Weight | 315.41 |
10
Verdiperstat, MedChemExpress
MedChemExpress Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
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| Molecular Weight (g/mol) | 253.32 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Verdiperstat |
| Grade | Research |
| SMILES | O=C(N1)C(NC=C2)=C2N(CCOC(C)C)C1=S |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.6% |
| CAS | 890655-80-8 |
| Solubility Information | DMSO : 150 mg/mL (592.14 mM; Need ultrasonic) |
| Synonym | AZD3241 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C11H15N3O2S |
| Formula Weight | 253.32 |
11
PFE-360, MedChemExpress
MedChemExpress PFE-360 (PF-06685360) is a potent, selective, brain penetrated and orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor with a mean IC50 of 2.3 nM in vivo.
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| Molecular Weight (g/mol) | 308.34 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | PFE-360 |
| Grade | Research |
| SMILES | N#CC1=CC(C2=CNC3=NC=NC(N4CCOCC4)=C32)=CN1C |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 98.04% |
| CAS | 1527475-61-1 |
| Solubility Information | DMSO : 10.42 mg/mL (33.79 mM; Need ultrasonic) |
| Synonym | PF-06685360 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H16N6O |
| Formula Weight | 308.34 |
12
GSK503, MedChemExpress
MedChemExpress GSK503 is a potent and specific inhibitor of EZH2 methyltransferase with Kiapp values of 3 to 27 nM.
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| Molecular Weight (g/mol) | 526.67 |
|---|---|
| Color | Light Gray |
| Physical Form | Solid |
| Chemical Name or Material | GSK503 |
| Grade | Research |
| SMILES | O=C(C1=CC(C2=CC=C(N3CCN(C)CC3)N=C2)=CC4=C1C(C)=CN4C(C)C)NCC5=C(C)C=C(C)NC5=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.73% |
| CAS | 1346572-63-1 |
| Solubility Information | DMSO : ≥ 44 mg/mL (83.54 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C31H38N6O2 |
| Formula Weight | 526.67 |
13
GSK2606414, MedChemExpress
MedChemExpress GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM.
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| Molecular Weight (g/mol) | 451.44 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | GSK2606414 |
| Grade | Research |
| SMILES | NC1=C2C(N(C)C=C2C3=CC4=C(N(C(CC5=CC=CC(C(F)(F)F)=C5)=O)CC4)C=C3)=NC=N1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.59% |
| CAS | 1337531-36-8 |
| Solubility Information | DMSO : ≥ 100 mg/mL (221.51 mM) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H20F3N5O |
| Formula Weight | 451.44 |
14
DMX-5804, MedChemExpress
MedChemExpress DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.
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| Molecular Weight (g/mol) | 361.39 |
|---|---|
| Color | Off-White |
| Physical Form | Powder |
| Chemical Name or Material | DMX-5804 |
| Grade | Research |
| SMILES | O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.49% |
| CAS | 2306178-56-1 |
| Solubility Information | DMSO : 125 mg/mL (345.89 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C21H19N3O3 |
| Formula Weight | 361.39 |
15
Nigakinone, MedChemExpress
MedChemExpress Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.
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