Benzenesulfonamides
Organic compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an amino group; considered the amide of benzenesulfonic acid.
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Percent Purity
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Physical Form
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Quantity
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1
NXT629, MedChemExpress
MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.
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| Molecular Weight (g/mol) | 609.78 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | NXT629 |
| Grade | Research |
| SMILES | O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.2% |
| CAS | 1454925-59-7 |
| Solubility Information | DMSO : 125 mg/mL (204.99 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C35H39N5O3S |
| Formula Weight | 609.78 |
2
Indisulam, MedChemExpress
MedChemExpress Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15.
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| Molecular Weight (g/mol) | 385.85 |
|---|---|
| Color | Light Nude |
| Physical Form | Solid |
| Chemical Name or Material | Indisulam |
| Grade | Research |
| SMILES | O=S(C1=CC=C(S(=O)(N)=O)C=C1)(NC2=CC=CC3=C2NC=C3Cl)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 165668-41-7 |
| Solubility Information | DMSO : 100 mg/mL (259.17 mM; Need ultrasonic) |
| Health Hazard 1 | H315∣H319 |
| Synonym | E 7070 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C14H12ClN3O4S2 |
| Formula Weight | 385.85 |
3
DT-061, MedChemExpress
MedChemExpress DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.
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| Molecular Weight (g/mol) | 520.52 |
|---|---|
| Color | White |
| Physical Form | Powder |
| Chemical Name or Material | DT-061 |
| Grade | Research |
| SMILES | O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@H]2[C@H](O)[C@@H](N3C4=C(C=CC=C4)OC5=CC=CC=C35)CCC2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.16% |
| CAS | 1809427-19-7 |
| Solubility Information | DMSO : 125 mg/mL (240.14 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C25H23F3N2O5S |
| Formula Weight | 520.52 |
4
HJC0350, MedChemExpress
MedChemExpress HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.
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| Molecular Weight (g/mol) | 277.38 |
|---|---|
| Color | Pink |
| Physical Form | Solid |
| Chemical Name or Material | HJC0350 |
| Grade | Research |
| SMILES | O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.52% |
| CAS | 885434-70-8 |
| Solubility Information | DMSO : 33.33 mg/mL (120.16 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H19NO2S |
| Formula Weight | 277.38 |
5
KI696 isomer, MedChemExpress
MedChemExpress KI696 isomer is the less active isomer of KI696 (HY-101140). KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction.
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| Molecular Weight (g/mol) | 550.63 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | KI696 isomer |
| Grade | Research |
| SMILES | COC1=C(N2C)C(N=N2)=CC([C@@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.44% |
| CAS | 1799974-69-8 |
| Solubility Information | DMSO : 125 mg/mL (227.01 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C28H30N4O6S |
| Formula Weight | 550.63 |
6
KP496, MedChemExpress
MedChemExpress KP496 is a selective, dual antagonist for Leukotriene D4 receptor and Thromboxane A2 receptor.
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7
GSK2981278, MedChemExpress
MedChemExpress GSK2981278 is a potent and selective RORγ inverse agonist. GSK2981278 inhibits activation of the il17 promoter and interferes RORγ-DNA binding.
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| Molecular Weight (g/mol) | 461.61 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | GSK2981278 |
| Grade | Research |
| SMILES | CC(C)CN(S(=O)(C1=CC=C(OCC2CCOCC2)C(CO)=C1)=O)C3=CC=C(CC)C=C3 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.33% |
| CAS | 1474110-21-8 |
| Solubility Information | DMSO : ≥ 100 mg/mL (216.63 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C25H35NO5S |
| Formula Weight | 461.61 |
8
Tolazamide, MedChemExpress
MedChemExpress Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes.
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| Molecular Weight (g/mol) | 311.4 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Tolazamide |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C)C=C1)(NC(NN2CCCCCC2)=O)=O |
| Percent Purity | 98.0% |
| CAS | 1156-19-0 |
| Solubility Information | DMSO : ≥ 39 mg/mL (125.24 mM) |
| Synonym | U-17835 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C14H21N3O3S |
| Formula Weight | 311.4 |
9
Chlorthalidone, MedChemExpress
MedChemExpress Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
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| Molecular Weight (g/mol) | 338.77 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Chlorthalidone |
| Grade | Research |
| SMILES | O=S(C1=CC(C2(O)NC(C3=C2C=CC=C3)=O)=CC=C1Cl)(N)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.76% |
| CAS | 77-36-1 |
| Solubility Information | DMSO : ≥ 41 mg/mL (121.03 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C14H11ClN2O4S |
| Formula Weight | 338.77 |
10
KM11060, MedChemExpress
MedChemExpress KM11060 is a corrector of the F508 deletion (F508del)-cystic fibrosis transmembrane conductance regulator (CFTR) trafficking defect. KM11060 can be used for the research of F508del-CFTR processing defect and development of cystic fibrosis therapeutics.
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| Molecular Weight (g/mol) | 422.33 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | KM11060 |
| Grade | Research |
| SMILES | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O |
| Percent Purity | 99.59% |
| CAS | 774549-97-2 |
| Solubility Information | DMSO : 50 mg/mL (118.39 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H17Cl2N3O2S |
| Formula Weight | 422.33 |
11
CaMKII-IN-1, MedChemExpress
MedChemExpress CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.
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| Molecular Weight (g/mol) | 548.1 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | CaMKII-IN-1 |
| Grade | Research |
| SMILES | O=S(C1=CC=CC(Cl)=C1C)(NC2=C(CN(CC3=CC=CC=C3)CC4)C4=NC(NCCC5=CC=CC=C5)=N2)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.74% |
| CAS | 1208123-85-6 |
| Solubility Information | DMSO : ≥ 54 mg/mL (98.52 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C29H30ClN5O2S |
| Formula Weight | 548.1 |
12
Indeglitazar, MedChemExpress
MedChemExpress Indeglitazar (PPM 204) is an orally available PPAR pan-agonist for all three PPARα, PPARδ and PPARγ.
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| Molecular Weight (g/mol) | 389.42 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | Indeglitazar |
| Grade | Research |
| SMILES | O=C(O)CCC1=CN(S(=O)(C2=CC=C(OC)C=C2)=O)C3=C1C=C(OC)C=C3 |
| For Use With (Application) | Metabolism-sugar/lipid metabolism |
| Percent Purity | 99.11% |
| CAS | 835619-41-5 |
| Solubility Information | DMSO : 100 mg/mL (256.79 mM; Need ultrasonic) |
| Synonym | PPM 204 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H19NO6S |
| Formula Weight | 389.42 |
13
SP2509, MedChemExpress
MedChemExpress SP2509 is a potent and selective antagonist of lysine specific demethylase 1 (LSD1) with an IC50 of 13 nM.
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| Molecular Weight (g/mol) | 437.9 |
|---|---|
| Color | White |
| Physical Form | Powder |
| Chemical Name or Material | SP2509 |
| Grade | Research |
| SMILES | O=C(N/N=C(C1=CC(Cl)=CC=C1O)\C)C2=CC=CC(S(=O)(N3CCOCC3)=O)=C2 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 97.72% |
| CAS | 1423715-09-6 |
| Solubility Information | DMSO : ≥ 33 mg/mL (75.36 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C19H20ClN3O5S |
| Formula Weight | 437.9 |
14
A-867744, MedChemExpress
MedChemExpress A-867744 is a highly potent and selective type II positive allosteric modulator (PAM) of the alpha7 nicotinic acetylcholine receptors (nAChR) with an EC50 of 1.0 μM.
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| Molecular Weight (g/mol) | 402.89 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | A-867744 |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C=C1)N2C(C)=C(C=C2C3=CC=C(C=C3)Cl)C(CC)=O)(N)=O |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 95.06% |
| CAS | 1000279-69-5 |
| Solubility Information | DMSO : ≥ 100 mg/mL (248.21 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H19ClN2O3S |
| Formula Weight | 402.89 |
15
AK-1, MedChemExpress
MedChemExpress AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC50 of 12.5 μM.
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| Molecular Weight (g/mol) | 403.45 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | AK-1 |
| Grade | Research |
| SMILES | O=C(NC1=CC=CC([N+]([O-])=O)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2 |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 99.8% |
| CAS | 330461-64-8 |
| Solubility Information | DMSO : ≥ 50 mg/mL (123.93 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H21N3O5S |
| Formula Weight | 403.45 |