NXT629, MedChemExpress

Product Code.	Quantity	unitSize
16477547	5 mg	5mg
16471067	50 mg	50mg
16415606	100 mg	100mg
16414808	10 mg	10mg
16403256	25 mg	25mg

Product Code. 16477547 Supplier Medchem Express Supplier No. HY114263

Description

MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

Spezifikation

• Chemical Name or Material: NXT629
• CAS: 1454925-59-7
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₃₅H₃₉N₅O₃S
• Quantity: 5 mg
• Solubility Information: DMSO : 125 mg/mL (204.99 mM; Need ultrasonic)
• SMILES: O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
• Molecular Weight (g/mol): 609.78
• Formula Weight: 609.78
• Percent Purity: 99.2%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only