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Pyrroles

Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.

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1 – 15 of 33 results
1

(S)-Ketorolac, MedChemExpress

MedChemExpress (S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potent COX1 and COX2 enzyme inhibition.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 255.27
Color Off-White
Physical Form Solid
Chemical Name or Material (S)-Ketorolac
Grade Research
SMILES O=C(C1=CC=CC=C1)C2=CC=C3N2CC[C@@H]3C(O)=O
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 99.62%
CAS 66635-92-5
Solubility Information DMSO : 200 mg/mL (783.48 mM; Need ultrasonic)
Synonym (-)-Ketorolac
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C15H13NO3
Formula Weight 255.27
2

2,5-Dimethyl-1-phenylpyrrole-3-carboxaldehyde, 98+%

CAS: 83-18-1 Molecular Formula: C13H13NO Molecular Weight (g/mol): 199.25 MDL Number: MFCD00051494 InChI Key: LNROIXNEIZSESG-UHFFFAOYSA-N Synonym: 2,5-dimethyl-1-phenyl-1h-pyrrole-3-carbaldehyde,2,5-dimethyl-1-phenylpyrrole-3-carboxaldehyde,1h-pyrrole-3-carboxaldehyde, 2,5-dimethyl-1-phenyl,2,5-dimethyl-1-phenyl-1h-pyrrole-3-carboxaldehyde,osm-s-28,10.14272/lnroixneizsesg-uhfffaoysa-n,2,5-dimethyl-1-phenyl-3-pyrrolecarboxaldehyde,pyrrole-3-carboxaldehyde,5-dimethyl-1-phenyl,2,5-dimethyl-1-phenyl pyrrole-3-carboxaldehyde,1-phenyl-2,5-dimethyl-1h-pyrrole-3-carbaldehyde PubChem CID: 66515 IUPAC Name: 2,5-dimethyl-1-phenylpyrrole-3-carbaldehyde SMILES: CC1=CC(C=O)=C(C)N1C1=CC=CC=C1

PubChem CID 66515
CAS 83-18-1
Molecular Weight (g/mol) 199.25
MDL Number MFCD00051494
SMILES CC1=CC(C=O)=C(C)N1C1=CC=CC=C1
Synonym 2,5-dimethyl-1-phenyl-1h-pyrrole-3-carbaldehyde,2,5-dimethyl-1-phenylpyrrole-3-carboxaldehyde,1h-pyrrole-3-carboxaldehyde, 2,5-dimethyl-1-phenyl,2,5-dimethyl-1-phenyl-1h-pyrrole-3-carboxaldehyde,osm-s-28,10.14272/lnroixneizsesg-uhfffaoysa-n,2,5-dimethyl-1-phenyl-3-pyrrolecarboxaldehyde,pyrrole-3-carboxaldehyde,5-dimethyl-1-phenyl,2,5-dimethyl-1-phenyl pyrrole-3-carboxaldehyde,1-phenyl-2,5-dimethyl-1h-pyrrole-3-carbaldehyde
IUPAC Name 2,5-dimethyl-1-phenylpyrrole-3-carbaldehyde
InChI Key LNROIXNEIZSESG-UHFFFAOYSA-N
Molecular Formula C13H13NO
3

Alflutinib mesylate, MedChemExpress

MedChemExpress Alflutinib (Furmonertinib) mesylate is is a potent inhibitor of EGFR. Alflutinib (Furmonertinib) mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Alflutinib (Furmonertinib) mesylate has the potential for the research of cancer diseases, especially non-small cell lung cancer (NSCLC).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 664.7
Color Yellow
Physical Form Solid
Chemical Name or Material Alflutinib mesylate
Grade Research
SMILES C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(CCN(C)C)C)=O.CS(=O)(O)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 99.89%
CAS 2130958-55-1
Solubility Information DMSO : 5 mg/mL (7.52 mM; Need ultrasonic)
Synonym Furmonertinib mesylateAST2818 mesylate
Purity Grade Notes Research
Recommended Storage 4°C, sealed storage, away from moisture∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life 4°C, sealed storage, away from moisture∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula C29H35F3N8O5S
Formula Weight 664.7
4

AM679, MedChemExpress

MedChemExpress AM679 is a potent, selective 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 2 nM in a human FLAP membrane binding assay. AM679 markedly reduces the respiratory syncytial virus-driven ocular pathology as well as the synthesis of cysteinyl leukotrienes (CysLTs) in the eye.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 692.87
Color pale pink
Physical Form Solid
Chemical Name or Material AM679
Grade Research
SMILES O=C(C)N1C2=CC=CC=C2C[C@H]1COC3=CC=C(N(CC4=CC=C(C5=NC=C(OC)C=N5)C=C4)C(CC(C)(C(O)=O)C)=C6SC(C)(C)C)C6=C3
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.6%
CAS 1206880-66-1
Solubility Information DMSO : ≥ 100 mg/mL (144.33 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C40H44N4O5S
Formula Weight 692.87
5

KY1220, MedChemExpress

MedChemExpress KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 314.32
Color Yellow
Physical Form Solid
Chemical Name or Material KY1220
Grade Research
SMILES O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 292168-79-7
Solubility Information DMSO : ≥ 100 mg/mL (318.15 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C14H10N4O3S
Formula Weight 314.32
6

Amcasertib, MedChemExpress

MedChemExpress Amcasertib (BBI503) is an orally active and small-molecule multi-kinase inhibitor. Amcasertib exhibits inhibitory activity against the NANOG and CD133 expression and cell viability in PC-9/GR cells. As an orally available cancer cell stemness kinase inhibitor with potential antineoplastic activity, it is currently being studied in phase I clinical trials in a number of cancers.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 539.69
Color Yellow
Physical Form Solid
Chemical Name or Material Amcasertib
Grade Research
SMILES O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.15%
CAS 1129403-56-0
Solubility Information DMSO : ≥ 30 mg/mL (55.59 mM)
Synonym BBI503
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C31H33N5O2S
Formula Weight 539.69
7

Verdiperstat, MedChemExpress

MedChemExpress Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 253.32
Color White
Physical Form Solid
Chemical Name or Material Verdiperstat
Grade Research
SMILES O=C(N1)C(NC=C2)=C2N(CCOC(C)C)C1=S
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 99.6%
CAS 890655-80-8
Solubility Information DMSO : 150 mg/mL (592.14 mM; Need ultrasonic)
Synonym AZD3241
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C11H15N3O2S
Formula Weight 253.32
8

AZD1981, MedChemExpress

MedChemExpress AZD1981 is a potent and selective CRTh2 antagonist; displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8.4).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 388.87
Color Gray
Physical Form Solid
Chemical Name or Material AZD1981
Grade Research
SMILES O=C(O)CN1C(C)=C(SC2=CC=C(Cl)C=C2)C3=C1C=CC=C3NC(C)=O
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.81%
CAS 802904-66-1
Solubility Information DMSO : ≥ 31 mg/mL (79.72 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H17ClN2O3S
Formula Weight 388.87
9

Ecopladib, MedChemExpress

MedChemExpress Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.

ENCOMPASS_PREFERRED
10

Pamicogrel, MedChemExpress

MedChemExpress Pamicogrel (KBT3022) is a cyclooxygenase (COX) inhibitor.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 448.53
Color Off-White
Physical Form Solid
Chemical Name or Material Pamicogrel
Grade Research
SMILES O=C(OCC)CN1C(C2=NC(C3=CC=C(OC)C=C3)=C(C4=CC=C(OC)C=C4)S2)=CC=C1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.0%
CAS 101001-34-7
Solubility Information DMSO : 83.33 mg/mL (185.78 mM; Need ultrasonic)
Synonym KBT3022
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C25H24N2O4S
Formula Weight 448.53
11

Fevipiprant, MedChemExpress

MedChemExpress Fevipiprant (QAW039; NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 426.41
Color White
Physical Form Solid
Chemical Name or Material Fevipiprant
Grade Research
SMILES O=C(O)CC1=C(C)N(CC2=CC=C(S(=O)(C)=O)C=C2C(F)(F)F)C3=NC=CC=C31
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.06%
CAS 872365-14-5
Solubility Information DMSO : ≥ 32 mg/mL (75.05 mM)
Synonym QAW039 NVP-QAW039
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H17F3N2O4S
Formula Weight 426.41
12

GSK-2881078, MedChemExpress

MedChemExpress GSK 2881078 is a selective androgen receptor modulator potentially for the treatment of cachexia.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 330.33
Color Off-White
Physical Form Powder
Chemical Name or Material GSK-2881078
Grade Research
SMILES N#CC1=C(C(F)(F)F)C2=C(N([C@H](C)CS(=O)(C)=O)C=C2)C=C1
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 99.74%
CAS 1539314-06-1
Solubility Information DMSO : ≥ 33 mg/mL (99.90 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C14H13F3N2O2S
Formula Weight 330.33
13

DC1SMe, MedChemExpress

MedChemExpress DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 684.23
Color Yellow
Physical Form Solid
Chemical Name or Material DC1SMe
Grade Research
SMILES O=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 501666-85-9
Purity Grade Notes Research
Recommended Storage -20°C, stored under nitrogen, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen, away from moisture)
Shelf Life -20°C, stored under nitrogen, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen, away from moisture)
Molecular Formula C35H30ClN5O4S2
Formula Weight 684.23
14

TEPP-46, MedChemExpress

MedChemExpress TEPP-46 (ML-265) is a potent and selective pyruvate kinase M2 (PKM2) activator with an AC50 of 92 nM, showing little or no effect on PKM1, PKL and PKR.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 372.46
Color Light Yellow
Physical Form Solid
Chemical Name or Material TEPP-46
Grade Research
SMILES O=C1C(N(C)C2=C3SC(S(C)=O)=C2)=C3C=NN1CC4=CC=CC(N)=C4
For Use With (Application) Cancer-Kinase/protease
Percent Purity 95.86%
CAS 1221186-53-3
Solubility Information DMSO : 50 mg/mL (134.24 mM; Need ultrasonic)
Synonym ML-265
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C17H16N4O2S2
Formula Weight 372.46
15

Beclabuvir, MedChemExpress

MedChemExpress Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 659.84
Color White
Physical Form Solid
Chemical Name or Material Beclabuvir
Grade Research
SMILES O=C(N1C2CCC1CN(C)C2)[C@@]3(CN4C5=C(C6CCCCC6)C7=CC=C(C(NS(N(C)C)(=O)=O)=O)C=C47)[C@H](C8=CC(OC)=CC=C85)C3
For Use With (Application) COVID-19-anti-virus
Percent Purity 99.87%
CAS 958002-33-0
Solubility Information DMSO : ≥ 30 mg/mL (45.47 mM)
Synonym BMS-791325
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C36H45N5O5S
Formula Weight 659.84