Piperidines

Organic heterocyclic compounds that consist of a six-membered ring containing five carbon atoms and one nitrogen atom that forms an amine functional group.

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1 – 15 of 200 results

(S)-(+)-3-Amino-1-Boc-piperidine, 97%

CAS: 625471-18-3 Molecular Formula: C10H20N2O2 Molecular Weight (g/mol): 200.28 MDL Number: MFCD03094718 InChI Key: AKQXKEBCONUWCL-UHFFFAOYNA-N Synonym: s-1-boc-3-aminopiperidine,s-3-amino-1-n-boc-piperidine,tert-butyl 3s-3-aminopiperidine-1-carboxylate,s-tert-butyl 3-aminopiperidine-1-carboxylate,s-3-amino-1-boc-piperidine,s-+-3-amino-1-boc-piperidine,3s-3-aminopiperidine, n1-boc protected,s-1-boc-3-amniopiperidine,s-3-amino-piperidine-1-carboxylic acid tert-butyl ester,s-3-amino-n-tboc-piperidine PubChem CID: 1501975 IUPAC Name: tert-butyl (3S)-3-aminopiperidine-1-carboxylate SMILES: CC(C)(C)OC(=O)N1CCCC(N)C1

Pricing and Availability
Specifications

PubChem CID	1501975
CAS	625471-18-3
Molecular Weight (g/mol)	200.28
MDL Number	MFCD03094718
SMILES	CC(C)(C)OC(=O)N1CCCC(N)C1
Synonym	s-1-boc-3-aminopiperidine,s-3-amino-1-n-boc-piperidine,tert-butyl 3s-3-aminopiperidine-1-carboxylate,s-tert-butyl 3-aminopiperidine-1-carboxylate,s-3-amino-1-boc-piperidine,s-+-3-amino-1-boc-piperidine,3s-3-aminopiperidine, n1-boc protected,s-1-boc-3-amniopiperidine,s-3-amino-piperidine-1-carboxylic acid tert-butyl ester,s-3-amino-n-tboc-piperidine
IUPAC Name	tert-butyl (3S)-3-aminopiperidine-1-carboxylate
InChI Key	AKQXKEBCONUWCL-UHFFFAOYNA-N
Molecular Formula	C10H20N2O2

2-Aminomethyl-1-Boc-piperidine, 95%

CAS: 370069-31-1 Molecular Formula: C11H22N2O2 Molecular Weight (g/mol): 214.309 MDL Number: MFCD01317791 InChI Key: PTVRCUVHYMGECC-UHFFFAOYSA-N Synonym: 2-aminomethyl-1-boc-piperidine,tert-butyl 2-aminomethyl piperidine-1-carboxylate,2-aminomethyl-1-n-boc-piperidine,1-boc-2-aminomethyl-piperidine,1-boc-2-aminomethyl piperidine,1-boc-2-aminomethylpiperidine,2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester,1-n-boc-2-aminomethyl piperidine PubChem CID: 2756482 IUPAC Name: tert-butyl 2-(aminomethyl)piperidine-1-carboxylate SMILES: CC(C)(C)OC(=O)N1CCCCC1CN

Pricing and Availability
Specifications

PubChem CID	2756482
CAS	370069-31-1
Molecular Weight (g/mol)	214.309
MDL Number	MFCD01317791
SMILES	CC(C)(C)OC(=O)N1CCCCC1CN
Synonym	2-aminomethyl-1-boc-piperidine,tert-butyl 2-aminomethyl piperidine-1-carboxylate,2-aminomethyl-1-n-boc-piperidine,1-boc-2-aminomethyl-piperidine,1-boc-2-aminomethyl piperidine,1-boc-2-aminomethylpiperidine,2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester,1-n-boc-2-aminomethyl piperidine
IUPAC Name	tert-butyl 2-(aminomethyl)piperidine-1-carboxylate
InChI Key	PTVRCUVHYMGECC-UHFFFAOYSA-N
Molecular Formula	C11H22N2O2

Gemigliptin, MedChemExpress

MedChemExpress Gemigliptin (LC15-0444 ) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin exhibits potent anti-glycation properties. Gemigliptin can be used for the research of advanced glycation end products (AGE)-related diabetic complications.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	489.36
Color	Orange
Physical Form	Solid
Chemical Name or Material	Gemigliptin
Grade	Research
SMILES	O=C1N(C[C@@H](N)CC(N2CCC3=C(C(F)(F)F)N=C(C(F)(F)F)N=C3C2)=O)CC(F)(F)CC1
For Use With (Application)	Metabolism-sugar/lipid metabolism
CAS	911637-19-9
Solubility Information	DMSO : 50 mg/mL (102.17 mM; Need ultrasonic)
Health Hazard 1	H302∣H335
Synonym	LC15-0444
Purity Grade Notes	Research
Recommended Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shelf Life	Please store the product under the recommended conditions in the Certificate of Analysis.
Molecular Formula	C₁₈H₁₉F₈N₅O₂
Formula Weight	489.36

Liproxstatin-1, MedChemExpress

MedChemExpress Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	340.85
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Liproxstatin-1
Grade	Research
SMILES	ClC1=CC(CNC2=NC3=CC=CC=C3NC24CCNCC4)=CC=C1
Percent Purity	97.13%
CAS	950455-15-9
Solubility Information	DMSO : ≥ 31 mg/mL (90.95 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₂₁ClN₄
Formula Weight	340.85

dBET6, MedChemExpress

MedChemExpress dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	841.37
Color	Off-White
Physical Form	Powder
Chemical Name or Material	dBET6
Grade	Research
SMILES	O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.12%
CAS	1950634-92-0
Solubility Information	DMSO : 50 mg/mL (59.43 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₄₂H₄₅ClN₈O₇S
Formula Weight	841.37

CC-885, MedChemExpress

MedChemExpress CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	440.88
Color	White
Physical Form	Solid
Chemical Name or Material	CC-885
Grade	Research
SMILES	O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.23%
CAS	1010100-07-8
Solubility Information	DMSO : 67.5 mg/mL (153.10 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₂₁ClN₄O₄
Formula Weight	440.88

b-AP15, MedChemExpress

MedChemExpress b-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	419.39
Color	Yellow
Physical Form	Solid
Chemical Name or Material	b-AP15
Grade	Research
SMILES	O=C1/C(CN(C(C=C)=O)C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=C/C3=CC=C([N+]([O-])=O)C=C3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.09%
CAS	1009817-63-3
Solubility Information	DMSO : 20 mg/mL (47.69 mM; Need ultrasonic)
Synonym	NSC 687852
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₂₂H₁₇N₃O₆
Formula Weight	419.39

JNJ-42153605, MedChemExpress

MedChemExpress JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	400.44
Color	White
Physical Form	Solid
Chemical Name or Material	JNJ-42153605
Grade	Research
SMILES	FC(C1=C(N2CCC(C3=CC=CC=C3)CC2)C=CN4C1=NN=C4CC5CC5)(F)F
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.24%
CAS	1254977-87-1
Solubility Information	DMSO : 16.67 mg/mL (41.63 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₂₃F₃N₄
Formula Weight	400.44

AZD-3463, MedChemExpress

MedChemExpress AZD-3463 (ALK/IGF1R inhibitor) is an orally active ALK/IGF1R inhibitor, with a Ki of 0.75 nM for ALK. AZD3463 induces apoptosis and autophagy in neuroblastoma cells.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	448.95
Color	Green
Physical Form	Solid
Chemical Name or Material	AZD-3463
Grade	Research
SMILES	ClC(C=NC(NC1=C(OC)C=C(N2CCC(N)CC2)C=C1)=N3)=C3C4=CNC5=C4C=CC=C5
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.27%
CAS	1356962-20-3
Solubility Information	DMSO : 20 mg/mL (44.55 mM; Need ultrasonic)
Synonym	ALK/IGF1R inhibitor
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₅ClN₆O
Formula Weight	448.95

Y-320, MedChemExpress

MedChemExpress Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	505.01
Color	Pink
Physical Form	Solid
Chemical Name or Material	Y-320
Grade	Research
SMILES	O=C(C1=C(C)N(C2=CC=C(Cl)C=C2)N=C1)NC3=CC=C(N4CCC(N5CCOCC5)CC4)C(C#N)=C3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.39%
CAS	288250-47-5
Solubility Information	DMSO : 5.5 mg/mL (10.89 mM; Need ultrasonic)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₉ClN₆O₂
Formula Weight	505.01

TAK-220, MedChemExpress

MedChemExpress TAK-220 is a selective and orally bioavailable CCR5 antagonist, with IC50s of 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively, but shows no effect on the binding to CCR1, CCR2b, CCR3, CCR4, or CCR7

Pricing and Availability
Specifications

Molecular Weight (g/mol)	553.14
Color	Off-White
Physical Form	Solid
Chemical Name or Material	TAK-220
Grade	Research
SMILES	O=C(C1CCN(C(C)=O)CC1)N(CCCN2CCC(CC3=CC=C(C(N)=O)C=C3)CC2)C4=CC=C(C)C(Cl)=C4
For Use With (Application)	COVID-19-anti-virus
Percent Purity	99.9%
CAS	333994-00-6
Solubility Information	DMSO : ≥ 50 mg/mL (90.39 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₁H₄₁ClN₄O₃
Formula Weight	553.14

GSK2200150A, MedChemExpress

MedChemExpress GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	357.47
Color	White
Physical Form	Solid
Chemical Name or Material	GSK2200150A
Grade	Research
SMILES	N1(CC2=CC=C(OCCO3)C3=C2)CCC4(C(C=CS5)=C5CCO4)CC1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.46%
CAS	1443138-53-1
Solubility Information	DMSO : 65 mg/mL (181.83 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₃NO₃S
Formula Weight	357.47

C25-140, MedChemExpress

MedChemExpress C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	457.57
Color	Off-White
Physical Form	Solid
Chemical Name or Material	C25-140
Grade	Research
SMILES	O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.12%
CAS	1358099-18-9
Solubility Information	DMSO : 41.67 mg/mL (91.07 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₃₁N₇O
Formula Weight	457.57

Glasdegib, MedChemExpress

MedChemExpress Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	374.44
Color	White
Physical Form	Powder
Chemical Name or Material	Glasdegib
Grade	Research
SMILES	O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.36%
CAS	1095173-27-5
Solubility Information	DMSO : ≥ 83.33 mg/mL (222.55 mM)
Synonym	PF-04449913
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₂N₆O
Formula Weight	374.44

Varenicline, MedChemExpress

MedChemExpress Varenicline (CP 526555) is a potent partial agonist for α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM. Varenicline is a full agonist for α3β4 and α7 nAChRs with EC50 values of 55 μM and 18 μM, respectively. Varenicline is a nicotinic ligand based on the structure of cytosine, and has the potential for smoking cessation treatment.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	211.26
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Varenicline
Grade	Research
SMILES	C12=C(C=C3N=CC=NC3=C2)C4CC1CNC4
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.98%
CAS	249296-44-4
Solubility Information	DMSO : 25 mg/mL (118.34 mM; Need ultrasonic)
Synonym	CP 526555
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₃H₁₃N₃
Formula Weight	211.26

Piperidines

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