Piperidines

Organic heterocyclic compounds that consist of a six-membered ring containing five carbon atoms and one nitrogen atom that forms an amine functional group.

1 – 15 of 200 results

(S)-(+)-3-Amino-1-Boc-piperidine, 97%

CAS: 625471-18-3 Molecular Formula: C10H20N2O2 Molecular Weight (g/mol): 200.28 MDL Number: MFCD03094718 InChI Key: AKQXKEBCONUWCL-UHFFFAOYNA-N Synonym: s-1-boc-3-aminopiperidine,s-3-amino-1-n-boc-piperidine,tert-butyl 3s-3-aminopiperidine-1-carboxylate,s-tert-butyl 3-aminopiperidine-1-carboxylate,s-3-amino-1-boc-piperidine,s-+-3-amino-1-boc-piperidine,3s-3-aminopiperidine, n1-boc protected,s-1-boc-3-amniopiperidine,s-3-amino-piperidine-1-carboxylic acid tert-butyl ester,s-3-amino-n-tboc-piperidine PubChem CID: 1501975 IUPAC Name: tert-butyl (3S)-3-aminopiperidine-1-carboxylate SMILES: CC(C)(C)OC(=O)N1CCCC(N)C1

Pricing and Availability
Specifications

PubChem CID	1501975
CAS	625471-18-3
Molecular Weight (g/mol)	200.28
MDL Number	MFCD03094718
SMILES	CC(C)(C)OC(=O)N1CCCC(N)C1
Synonym	s-1-boc-3-aminopiperidine,s-3-amino-1-n-boc-piperidine,tert-butyl 3s-3-aminopiperidine-1-carboxylate,s-tert-butyl 3-aminopiperidine-1-carboxylate,s-3-amino-1-boc-piperidine,s-+-3-amino-1-boc-piperidine,3s-3-aminopiperidine, n1-boc protected,s-1-boc-3-amniopiperidine,s-3-amino-piperidine-1-carboxylic acid tert-butyl ester,s-3-amino-n-tboc-piperidine
IUPAC Name	tert-butyl (3S)-3-aminopiperidine-1-carboxylate
InChI Key	AKQXKEBCONUWCL-UHFFFAOYNA-N
Molecular Formula	C10H20N2O2

2-Aminomethyl-1-Boc-piperidine, 95%

CAS: 370069-31-1 Molecular Formula: C11H22N2O2 Molecular Weight (g/mol): 214.309 MDL Number: MFCD01317791 InChI Key: PTVRCUVHYMGECC-UHFFFAOYSA-N Synonym: 2-aminomethyl-1-boc-piperidine,tert-butyl 2-aminomethyl piperidine-1-carboxylate,2-aminomethyl-1-n-boc-piperidine,1-boc-2-aminomethyl-piperidine,1-boc-2-aminomethyl piperidine,1-boc-2-aminomethylpiperidine,2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester,1-n-boc-2-aminomethyl piperidine PubChem CID: 2756482 IUPAC Name: tert-butyl 2-(aminomethyl)piperidine-1-carboxylate SMILES: CC(C)(C)OC(=O)N1CCCCC1CN

Pricing and Availability
Specifications

PubChem CID	2756482
CAS	370069-31-1
Molecular Weight (g/mol)	214.309
MDL Number	MFCD01317791
SMILES	CC(C)(C)OC(=O)N1CCCCC1CN
Synonym	2-aminomethyl-1-boc-piperidine,tert-butyl 2-aminomethyl piperidine-1-carboxylate,2-aminomethyl-1-n-boc-piperidine,1-boc-2-aminomethyl-piperidine,1-boc-2-aminomethyl piperidine,1-boc-2-aminomethylpiperidine,2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester,1-n-boc-2-aminomethyl piperidine
IUPAC Name	tert-butyl 2-(aminomethyl)piperidine-1-carboxylate
InChI Key	PTVRCUVHYMGECC-UHFFFAOYSA-N
Molecular Formula	C11H22N2O2

Gemigliptin, MedChemExpress

MedChemExpress Gemigliptin (LC15-0444 ) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin exhibits potent anti-glycation properties. Gemigliptin can be used for the research of advanced glycation end products (AGE)-related diabetic complications.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	489.36
Color	Orange
Physical Form	Solid
Chemical Name or Material	Gemigliptin
Grade	Research
SMILES	O=C1N(C[C@@H](N)CC(N2CCC3=C(C(F)(F)F)N=C(C(F)(F)F)N=C3C2)=O)CC(F)(F)CC1
For Use With (Application)	Metabolism-sugar/lipid metabolism
CAS	911637-19-9
Solubility Information	DMSO : 50 mg/mL (102.17 mM; Need ultrasonic)
Health Hazard 1	H302∣H335
Synonym	LC15-0444
Purity Grade Notes	Research
Recommended Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shelf Life	Please store the product under the recommended conditions in the Certificate of Analysis.
Molecular Formula	C₁₈H₁₉F₈N₅O₂
Formula Weight	489.36

b-AP15, MedChemExpress

MedChemExpress b-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	419.39
Color	Yellow
Physical Form	Solid
Chemical Name or Material	b-AP15
Grade	Research
SMILES	O=C1/C(CN(C(C=C)=O)C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=C/C3=CC=C([N+]([O-])=O)C=C3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.09%
CAS	1009817-63-3
Solubility Information	DMSO : 20 mg/mL (47.69 mM; Need ultrasonic)
Synonym	NSC 687852
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₂₂H₁₇N₃O₆
Formula Weight	419.39

TD-106, MedChemExpress

MedChemExpress TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	273.25
Color	Yellow
Physical Form	Solid
Chemical Name or Material	TD-106
Grade	Research
SMILES	NC1=CC=CC(N=NN2C3CCC(NC3=O)=O)=C1C2=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.17%
CAS	2250288-69-6
Solubility Information	DMSO : ≥ 125 mg/mL (457.46 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₂H₁₁N₅O₃
Formula Weight	273.25

Navtemadlin, MedChemExpress

MedChemExpress Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	568.55
Color	White
Physical Form	Powder
Chemical Name or Material	Navtemadlin
Grade	Research
SMILES	O=C(O)C[C@]1(C)C(N([C@H](CS(=O)(C(C)C)=O)C(C)C)[C@H](C2=CC=C(Cl)C=C2)[C@@H](C3=CC=CC(Cl)=C3)C1)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	96.04%
CAS	1352066-68-2
Solubility Information	DMSO : ≥ 50 mg/mL (87.94 mM) ∣H2O : ≥ 0.1 mg/mL (0.18 mM)
Synonym	AMG 232 KRT-232
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₂₈H₃₅Cl₂NO₅S
Formula Weight	568.55

JNJ-40411813, MedChemExpress

MedChemExpress JNJ-40411813 (ADX-71149) is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	344.88
Color	White
Physical Form	Solid
Chemical Name or Material	JNJ-40411813
Grade	Research
SMILES	O=C1C(Cl)=C(N2CCC(C3=CC=CC=C3)CC2)C=CN1CCCC
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.97%
CAS	1127498-03-6
Solubility Information	DMSO : 25 mg/mL (72.49 mM; Need ultrasonic)
Synonym	ADX-71149
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₅ClN₂O
Formula Weight	344.88

Bemegride, MedChemExpress

MedChemExpress Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	155.19
Color	White
Physical Form	Solid
Chemical Name or Material	Bemegride
Grade	Research
SMILES	O=C(CC(C)(CC)C1)NC1=O
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.92%
CAS	64-65-3
Solubility Information	DMSO : ≥ 32 mg/mL (206.20 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	3-Ethyl-3-methylglutarimide Bemegrid
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₈H₁₃NO₂
Formula Weight	155.19

(S)-SNAP5114, MedChemExpress

MedChemExpress (S)-SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant drug.

Pricing and Availability

BIBF0775, MedChemExpress

MedChemExpress BIBF0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor with an IC50 of 34 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	494.63
Color	Yellow
Physical Form	Solid
Chemical Name or Material	BIBF0775
Grade	Research
SMILES	O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(C3=CC=CC=C3)\NC4=CC=C(CN5CCCCC5)C=C4)N(CC)C
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.53%
CAS	334951-90-5
Solubility Information	DMSO : 62.5 mg/mL (126.36 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₁H₃₄N₄O₂
Formula Weight	494.63

GSK 4027, MedChemExpress

MedChemExpress GSK 4027 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC50 of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	377.28
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GSK 4027
Grade	Research
SMILES	BrC1=C(N[C@@H]2C[C@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.8%
CAS	2079896-25-4
Solubility Information	DMSO : 50 mg/mL (132.53 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₇H₂₁BrN₄O
Formula Weight	377.28

IPSU, MedChemExpress

MedChemExpress IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pKi of 7.85.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	405.49
Color	White
Physical Form	Solid
Chemical Name or Material	IPSU
Grade	Research
SMILES	COC1=CC=NC(N(CC2)CCC2(C3=O)CCCN3CC4=CNC5=CC=CC=C54)=N1
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.1%
CAS	1373765-19-5
Solubility Information	DMSO : ≥ 30 mg/mL (73.98 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₇N₅O₂
Formula Weight	405.49

CCG-203971, MedChemExpress

MedChemExpress CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	408.88
Color	White
Physical Form	Solid
Chemical Name or Material	CCG-203971
Grade	Research
SMILES	O=C(C1CN(C(C2=CC=CC(C3=CC=CO3)=C2)=O)CCC1)NC4=CC=C(Cl)C=C4
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.0%
CAS	1443437-74-8
Solubility Information	DMSO : 250 mg/mL (611.43 mM; Need ultrasonic)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₁ClN₂O₃
Formula Weight	408.88

PROTAC CDK9 Degrader-1, MedChemExpress

MedChemExpress PROTAC CDK9 Degrader-1 is a PROTAC connected by ligands for Cereblon and CDK as a selective CDK9 degrader.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	613.66
Color	White
Physical Form	Solid
Chemical Name or Material	PROTAC CDK9 Degrader-1
Grade	Research
SMILES	O=C(CC1=CC=C(OCCCCCOC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O)C=C1)NC5=CC(C6CCC6)=NN5
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.01%
CAS	2118356-96-8
Solubility Information	DMSO : ≥ 104 mg/mL (169.47 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₃H₃₅N₅O₇
Formula Weight	613.66

GSK4028, MedChemExpress

MedChemExpress GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	377.28
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GSK4028
Grade	Research
SMILES	BrC1=C(N[C@H]2C[C@@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.55%
CAS	2079886-19-2
Solubility Information	DMSO : 100 mg/mL (265.06 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₇H₂₁BrN₄O
Formula Weight	377.28

Piperidines

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