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Filtered Search Results
Tilfrinib, MedChemExpress
MedChemExpress Tilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent.
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NSC 74859, MedChemExpress
MedChemExpress NSC 74859 (S3I-201) is a selective Stat3 inhibitor with an IC50 of 86 μM.
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| Molecular Weight (g/mol) | 365.36 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | NSC 74859 |
| Grade | Research |
| SMILES | OC1=CC(NC(COS(=O)(C2=CC=C(C=C2)C)=O)=O)=CC=C1C(O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.01% |
| CAS | 501919-59-1 |
| Solubility Information | DMSO : 100 mg/mL (273.70 mM; Need ultrasonic) |
| Synonym | S3I-201 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended. |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended. |
| Molecular Formula | C16H15NO7S |
| Formula Weight | 365.36 |
Troglitazone, MedChemExpress
MedChemExpress Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
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| Molecular Weight (g/mol) | 441.54 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Troglitazone |
| Grade | Research |
| SMILES | O=C(SC1CC(C=C2)=CC=C2OCC3(C)OC(C(CC3)=C4C)=C(C)C(C)=C4O)NC1=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 96.46% |
| CAS | 97322-87-7 |
| Solubility Information | DMSO : 160 mg/mL (362.37 mM; Need ultrasonic) |
| Synonym | CS-045 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H27NO5S |
| Formula Weight | 441.54 |
Acetosyringone, MedChemExpress
MedChemExpress Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains.
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Didox, MedChemExpress
MedChemExpress Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.
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| Molecular Weight (g/mol) | 169.13 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Didox |
| Grade | Research |
| SMILES | O=C(NO)C1=CC=C(O)C(O)=C1 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 69839-83-4 |
| Solubility Information | DMSO : 100 mg/mL (591.26 mM; Need ultrasonic) |
| Synonym | NSC-324360 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C7H7NO4 |
| Formula Weight | 169.13 |
FX-11, MedChemExpress
MedChemExpress FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) specific inhibitor, with a Ki of 8 μM. FX-11 can effectively activate PKM2 (pyruvate kinase M2). FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts.
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| Molecular Weight (g/mol) | 350.41 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | FX-11 |
| Grade | Research |
| SMILES | O=C(C1=C2C=C(CC3=CC=CC=C3)C(C)=CC2=C(CCC)C(O)=C1O)O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.44% |
| CAS | 213971-34-7 |
| Solubility Information | DMSO : 250 mg/mL (713.45 mM; Need ultrasonic) |
| Synonym | LDHA Inhibitor FX11 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C22H22O4 |
| Formula Weight | 350.41 |
AGI-24512, MedChemExpress
MedChemExpress AGI-24512 is a potent methionine adenosyltransferase 2α (MAT2A) inhibitor, with an IC50 of 8 nM. AGI-24512 triggers DNA damage response. AGI-24512 can block proliferation of MTAP-deleted cancer cells in vitro. AGI-24512 can be used for researching anticancer.
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| Molecular Weight (g/mol) | 400.47 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | AGI-24512 |
| Grade | Research |
| SMILES | O=C1C(C2=CC=C(O)C=C2)=C(C)NC3=C(N4CCCCC4)C(C5=CC=CC=C5)=NN13 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.48% |
| CAS | 2201066-53-5 |
| Solubility Information | DMSO : 125 mg/mL (312.13 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H24N4O2 |
| Formula Weight | 400.47 |
Oxidopamine hydrobromide, MedChemExpress
MedChemExpress Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine.
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| Molecular Weight (g/mol) | 250.09 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | Oxidopamine hydrobromide |
| Grade | Research |
| SMILES | OC1=CC(CCN)=C(O)C=C1O.[H]Br |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 636-00-0 |
| Solubility Information | DMSO : 50 mg/mL (199.93 mM; ultrasonic and warming and heat to 60°C) ∣H2O : 20 mg/mL (79.97 mM; Need ultrasonic) |
| Synonym | 6-Hydroxydopamine hydrobromide 6-OHDA hydrobromide |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended. |
| Shelf Life | 4°C, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended. |
| Molecular Formula | C8H12BrNO3 |
| Formula Weight | 250.09 |
SP-420, MedChemExpress
MedChemExpress SP-420 is a desferrithiocin analogue with iron-clearing efficiency with ICE value of 26.7; more potent than desferrithiocin.
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| Molecular Weight (g/mol) | 355.41 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | SP-420 |
| Grade | Research |
| SMILES | O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O |
| Percent Purity | 99.68% |
| CAS | 911714-45-9 |
| Solubility Information | DMSO : ≥ 38 mg/mL (106.92 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H21NO6S |
| Formula Weight | 355.41 |
7,8-Dihydroxyflavone, MedChemExpress
MedChemExpress 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases.
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Salmeterol, MedChemExpress
MedChemExpress Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
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| Molecular Weight (g/mol) | 415.57 |
|---|---|
| Color | White |
| Physical Form | Powder |
| Chemical Name or Material | Salmeterol |
| Grade | Research |
| SMILES | OC1=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO |
| Percent Purity | 98.72% |
| CAS | 89365-50-4 |
| Solubility Information | DMSO : ≥ 100 mg/mL (240.63 mM) |
| Synonym | GR33343X |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C25H37NO4 |
| Formula Weight | 415.57 |
Plicamycin, MedChemExpress
MedChemExpress Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.
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| Molecular Weight (g/mol) | 1085.15 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Plicamycin |
| Grade | Research |
| SMILES | O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(C)C(O)=C85)=C8O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 18378-89-7 |
| Solubility Information | DMSO : ≥ 100 mg/mL (92.15 mM) |
| Health Hazard 1 | H302 |
| Synonym | Mithramycin A |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C52H76O24 |
| Formula Weight | 1085.15 |
3,4-Dihydroxymandelic acid, MedChemExpress
MedChemExpress 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.
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STF-083010, MedChemExpress
MedChemExpress STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
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| Molecular Weight (g/mol) | 317.38 |
|---|---|
| Color | Yellow |
| Physical Form | Powder |
| Chemical Name or Material | STF-083010 |
| Grade | Research |
| SMILES | O=S(C1=CC=CS1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.0% |
| CAS | 307543-71-1 |
| Solubility Information | DMSO : 100 mg/mL (315.08 mM; Need ultrasonic) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H11NO3S2 |
| Formula Weight | 317.38 |
C29, MedChemExpress
MedChemExpress C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocks hTLR2/1 and hTLR2/6 signaling with IC50s of 19.7 and 37.6 μM, respectively.
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| Molecular Weight (g/mol) | 285.29 |
|---|---|
| Color | Orange |
| Physical Form | Solid |
| Chemical Name or Material | C29 |
| Grade | Research |
| SMILES | OC1=C(/C=N/C2=C(C)C(C(O)=O)=CC=C2)C=CC=C1OC |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 363600-92-4 |
| Solubility Information | DMSO : ≥ 30 mg/mL (105.16 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15NO4 |
| Formula Weight | 285.29 |