Benzenesulfonyl compounds

Organosulfur compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an organic functional group.

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1 – 15 of 28 results

4,4'-Diaminodiphenyl sulfone, 98%

CAS: 80-08-0 Molecular Formula: C12H12N2O2S Molecular Weight (g/mol): 248.3 MDL Number: MFCD00007887 InChI Key: MQJKPEGWNLWLTK-UHFFFAOYSA-N Synonym: dapsone,diaphenylsulfone,4,4'-diaminodiphenyl sulfone,dapson,4,4'-sulfonyldianiline,diaphenylsulfon,sulfona,4-aminophenyl sulfone,avlosulfone,diphenasone PubChem CID: 2955 ChEBI: CHEBI:4325 IUPAC Name: 4-(4-aminophenyl)sulfonylaniline SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

Pricing and Availability
Specifications

PubChem CID	2955
CAS	80-08-0
Molecular Weight (g/mol)	248.3
ChEBI	CHEBI:4325
MDL Number	MFCD00007887
SMILES	C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
Synonym	dapsone,diaphenylsulfone,4,4'-diaminodiphenyl sulfone,dapson,4,4'-sulfonyldianiline,diaphenylsulfon,sulfona,4-aminophenyl sulfone,avlosulfone,diphenasone
IUPAC Name	4-(4-aminophenyl)sulfonylaniline
InChI Key	MQJKPEGWNLWLTK-UHFFFAOYSA-N
Molecular Formula	C12H12N2O2S

Stattic, MedChemExpress

MedChemExpress Stattic is a potent STAT3 inhibitor and inhibits STAT3 phosphorylation (at Y705 and S727). Stattic inhibits the binding of a high affinity phosphopeptide for the SH2 domain of STAT3. Stattic ameliorates the renal dysfunction in Alport syndrome (AS) mice.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	211.19
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Stattic
Grade	Research
SMILES	O=[N+](C1=CC=C(C=CS2(=O)=O)C2=C1)[O-]
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	97.0%
CAS	19983-44-9
Solubility Information	DMSO : 50 mg/mL (236.75 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₈H₅NO₄S
Formula Weight	211.19

BAY 11-7082, MedChemExpress

MedChemExpress BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	207.25
Color	White
Physical Form	Powder
Chemical Name or Material	BAY 11-7082
Grade	Research
SMILES	N#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.28%
CAS	19542-67-7
Solubility Information	DMSO : ≥ 100 mg/mL (482.51 mM)
Synonym	BAY 11-7821
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₀H₉NO₂S
Formula Weight	207.25

Imrecoxib, MedChemExpress

MedChemExpress Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor with an IC50 value of 18 nM, it also inhibits COX1- activity with an IC50 value of 115 nM. Imrecoxib (BAP-909) has anti-inflammatory effect.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	369.48
Color	White
Physical Form	Powder
Chemical Name or Material	Imrecoxib
Grade	Research
SMILES	O=C1N(CCC)CC(C2=CC=C(S(=O)(C)=O)C=C2)=C1C3=CC=C(C)C=C3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.64%
CAS	395683-14-4
Solubility Information	DMSO : 100 mg/mL (270.65 mM; Need ultrasonic)
Synonym	BAP-909
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₃NO₃S
Formula Weight	369.48

BTB-1, MedChemExpress

MedChemExpress BTB-1 is a potent, selective and reversible mitotic motor protein Kif18A inhibitor with an IC50 of 1.69 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	297.71
Color	White
Physical Form	Solid
Chemical Name or Material	BTB-1
Grade	Research
SMILES	O=S(C1=CC=C(Cl)C=C1[N+]([O-])=O)(C2=CC=CC=C2)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.69%
CAS	86030-08-2
Solubility Information	DMSO : ≥ 100 mg/mL (335.90 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₂H₈ClNO₄S
Formula Weight	297.71

NNC-0640, MedChemExpress

MedChemExpress NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM.

Pricing and Availability

GSK2801, MedChemExpress

MedChemExpress GSK2801 is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	371.45
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GSK2801
Grade	Research
SMILES	O=C(C)C1=CC(C2=C(S(=O)(C)=O)C=CC=C2)=C3N1C=CC(OCCC)=C3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	95.0%
CAS	1619994-68-1
Solubility Information	DMSO : 50 mg/mL (134.61 mM; Need ultrasonic)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₁NO₄S
Formula Weight	371.45

STF-118804, MedChemExpress

MedChemExpress STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	461.53
Color	White
Physical Form	Solid
Chemical Name or Material	STF-118804
Grade	Research
SMILES	O=C(NCC1=CC=CN=C1)C2=CC=C(C3=NC(CS(=O)(C4=CC=C(C)C=C4)=O)=C(C)O3)C=C2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.03%
CAS	894187-61-2
Solubility Information	DMSO : ≥ 31 mg/mL (67.17 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₃N₃O₄S
Formula Weight	461.53

AZD-0284, MedChemExpress

MedChemExpress AZD-0284 is a selective inverse agonist of the nuclear receptor RORγ. AZD-0284 has the potential for plaque psoriasis vulgaris and respiratory tract disorders treatment.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	524.43
Color	Off-White
Physical Form	Solid
Chemical Name or Material	AZD-0284
Grade	Research
SMILES	O=C([C@@H]1N(C(C)=O)CC2=C1C=CC(S(=O)(C)=O)=C2)NC3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.84%
CAS	2101291-07-8
Solubility Information	DMSO : 100 mg/mL (190.68 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₂₁H₁₈F₆N₂O₅S
Formula Weight	524.43

Globalagliatin, MedChemExpress

MedChemExpress Globalagliatin (LY2608204) is a activator of glucokinase (GK) with EC50 of 42 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	559.81
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Globalagliatin
Grade	Research
SMILES	O=C([C@@]1(C2=CC=C(S(=O)(C3CC3)=O)C=C2)[C@H](C4CCCCC4)C1)NC5=NC=C(SCCN6CCCC6)S5
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	98.0%
CAS	1234703-40-2
Solubility Information	DMSO : ≥ 100 mg/mL (178.63 mM)
Synonym	LY2608204
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₃₇N₃O₃S₃
Formula Weight	559.81

BAY-85-8501, MedChemExpress

MedChemExpress BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	474.46
Color	Off-White
Physical Form	Solid
Chemical Name or Material	BAY-85-8501
Grade	Research
SMILES	N#CC1=C(C)N(C2=CC=CC(C(F)(F)F)=C2)C(N(C)[C@@H]1C3=CC=C(C#N)C=C3S(=O)(C)=O)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.24%
CAS	1161921-82-9
Solubility Information	DMSO : 200 mg/mL (421.53 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₁₇F₃N₄O₃S
Formula Weight	474.46

AZD7545, MedChemExpress

MedChemExpress AZD7545 is a potent, competitive, selective PDHK2 (pyruvate dehydrogenase kinase 2) inhibitor with IC50s of 36.8 nM, 6.4 nM for PDHK1 and PDHK2, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	478.87
Color	White
Physical Form	Solid
Chemical Name or Material	AZD7545
Grade	Research
SMILES	O=C(N(C)C)C1=CC=C(S(=O)(C2=CC=C(NC([C@@](C)(O)C(F)(F)F)=O)C(Cl)=C2)=O)C=C1
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	99.91%
CAS	252017-04-2
Solubility Information	DMSO : ≥ 46 mg/mL (96.06 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₈ClF₃N₂O₅S
Formula Weight	478.87

Rimeporide, MedChemExpress

MedChemExpress Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	333.38
Color	White
Physical Form	Solid
Chemical Name or Material	Rimeporide
Grade	Research
SMILES	O=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	98.0%
CAS	187870-78-6
Solubility Information	DMSO : 20 mg/mL (59.99 mM; Need ultrasonic and warming)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	EMD-87580
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₁H₁₅N₃O₅S₂
Formula Weight	333.38

Intepirdine, MedChemExpress

MedChemExpress Intepirdine (SB742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	353.44
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Intepirdine
Grade	Research
SMILES	O=S(C1=CC=CC=C1)(C2=CC(C=CC=C3N4CCNCC4)=C3N=C2)=O
For Use With (Application)	Neuroscience-Neurodegeneration
Percent Purity	98.06%
CAS	607742-69-8
Solubility Information	DMSO : 50 mg/mL (141.47 mM; Need ultrasonic)
Synonym	SB-742457 GSK-742457 RVT-101
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₉N₃O₂S
Formula Weight	353.44

BAY-8002, MedChemExpress

MedChemExpress BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	415.85
Color	White
Physical Form	Solid
Chemical Name or Material	BAY-8002
Grade	Research
SMILES	O=C(O)C1=CC=CC=C1NC(C2=CC(S(=O)(C3=CC=CC=C3)=O)=CC=C2Cl)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.1%
CAS	724440-27-1
Solubility Information	DMSO : 125 mg/mL (300.59 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₄ClNO₅S
Formula Weight	415.85

Benzenesulfonyl compounds

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