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Pyrroles

Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.

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1 – 15 of 56 results
1

5-Bromo-2-phenyl-7-azaindole, 97%, Thermo Scientific Chemicals

CAS: 953414-75-0 Molecular Formula: C13H9BrN2 Molecular Weight (g/mol): 273.13 MDL Number: MFCD11109822 InChI Key: QLKZJMXSXCDCCF-UHFFFAOYSA-N Synonym: 5-bromo-2-phenyl-1h-pyrrolo 2,3-b pyridine,5-bromo-2-phenyl-7-azaindole,1h-pyrrolo 2,3-b pyridine,5-bromo-2-phenyl,2-phenyl-5-bromo-1h-pyrrolo 2,3-b pyridine PubChem CID: 23643607 IUPAC Name: 5-bromo-2-phenyl-1H-pyrrolo[2,3-b]pyridine SMILES: BrC1=CN=C2NC(=CC2=C1)C1=CC=CC=C1

PubChem CID 23643607
CAS 953414-75-0
Molecular Weight (g/mol) 273.13
MDL Number MFCD11109822
SMILES BrC1=CN=C2NC(=CC2=C1)C1=CC=CC=C1
Synonym 5-bromo-2-phenyl-1h-pyrrolo 2,3-b pyridine,5-bromo-2-phenyl-7-azaindole,1h-pyrrolo 2,3-b pyridine,5-bromo-2-phenyl,2-phenyl-5-bromo-1h-pyrrolo 2,3-b pyridine
IUPAC Name 5-bromo-2-phenyl-1H-pyrrolo[2,3-b]pyridine
InChI Key QLKZJMXSXCDCCF-UHFFFAOYSA-N
Molecular Formula C13H9BrN2
2

Pyrrole-3-carboxylic acid hydrate, 95%

CAS: 336100-46-0 Molecular Formula: C5H5NO2 Molecular Weight (g/mol): 111.10 MDL Number: MFCD06201862 InChI Key: DOYOPBSXEIZLRE-UHFFFAOYSA-N Synonym: pyrrole-3-carboxylic acid hydrate,1h-pyrrole-3-carboxylic acid hydrate,c5h5no2.h2o,1h-pyrrole-3-carboxylicacid, hydrate 1:? PubChem CID: 45076181 IUPAC Name: 1H-pyrrole-3-carboxylic acid;hydrate SMILES: OC(=O)C1=CNC=C1

PubChem CID 45076181
CAS 336100-46-0
Molecular Weight (g/mol) 111.10
MDL Number MFCD06201862
SMILES OC(=O)C1=CNC=C1
Synonym pyrrole-3-carboxylic acid hydrate,1h-pyrrole-3-carboxylic acid hydrate,c5h5no2.h2o,1h-pyrrole-3-carboxylicacid, hydrate 1:?
IUPAC Name 1H-pyrrole-3-carboxylic acid;hydrate
InChI Key DOYOPBSXEIZLRE-UHFFFAOYSA-N
Molecular Formula C5H5NO2
5

Dirlotapide, MedChemExpress

MedChemExpress Dirlotapide (CP742033) is a gut-selective inhibitor of microsomal triglyceride transfer protein (MTP) that reliably produces weight loss in obese dogs.

ENCOMPASS_PREFERRED
6

Vinburnine, MedChemExpress

MedChemExpress Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.

ENCOMPASS_PREFERRED
7

SB269652, MedChemExpress

MedChemExpress SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology.

ENCOMPASS_PREFERRED
8

Apyramide, MedChemExpress

MedChemExpress Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 490.93
Color White
Physical Form Solid
Chemical Name or Material Apyramide
Grade Research
SMILES O=C(OC1=CC=C(NC(C)=O)C=C1)CC2=C(C)N(C(C3=CC=C(Cl)C=C3)=O)C4=C2C=C(OC)C=C4
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.06%
CAS 68483-33-0
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H23ClN2O5
Formula Weight 490.93
9

AM679, MedChemExpress

MedChemExpress AM679 is a potent, selective 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 2 nM in a human FLAP membrane binding assay. AM679 markedly reduces the respiratory syncytial virus-driven ocular pathology as well as the synthesis of cysteinyl leukotrienes (CysLTs) in the eye.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 692.87
Color pale pink
Physical Form Solid
Chemical Name or Material AM679
Grade Research
SMILES O=C(C)N1C2=CC=CC=C2C[C@H]1COC3=CC=C(N(CC4=CC=C(C5=NC=C(OC)C=N5)C=C4)C(CC(C)(C(O)=O)C)=C6SC(C)(C)C)C6=C3
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.6%
CAS 1206880-66-1
Solubility Information DMSO : ≥ 100 mg/mL (144.33 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C40H44N4O5S
Formula Weight 692.87
10

UNC2025, MedChemExpress

MedChemExpress UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 exhibits an excellent PK properties, and can be used for the investigation of acute leukemia.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 476.66
Color White
Physical Form Solid
Chemical Name or Material UNC2025
Grade Research
SMILES CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C53)C=C2)CC1
For Use With (Application) Cancer-Kinase/protease
Percent Purity 96.86%
CAS 1429881-91-3
Solubility Information DMSO : 33.33 mg/mL (69.92 mM; Need ultrasonic and warming)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C28H40N6O
Formula Weight 476.66
11

Ribociclib, MedChemExpress

MedChemExpress Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 434.54
Color Light Yellow
Physical Form Powder
Chemical Name or Material Ribociclib
Grade Research
SMILES O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5
For Use With (Application) Cancer-Kinase/protease
Percent Purity 99.52%
CAS 1211441-98-3
Solubility Information DMSO : 20 mg/mL (46.03 mM; Need ultrasonic)
Synonym LEE011
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H30N8O
Formula Weight 434.54
12

KY1220, MedChemExpress

MedChemExpress KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 314.32
Color Yellow
Physical Form Solid
Chemical Name or Material KY1220
Grade Research
SMILES O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 292168-79-7
Solubility Information DMSO : ≥ 100 mg/mL (318.15 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C14H10N4O3S
Formula Weight 314.32
13

Amcasertib, MedChemExpress

MedChemExpress Amcasertib (BBI503) is an orally active and small-molecule multi-kinase inhibitor. Amcasertib exhibits inhibitory activity against the NANOG and CD133 expression and cell viability in PC-9/GR cells. As an orally available cancer cell stemness kinase inhibitor with potential antineoplastic activity, it is currently being studied in phase I clinical trials in a number of cancers.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 539.69
Color Yellow
Physical Form Solid
Chemical Name or Material Amcasertib
Grade Research
SMILES O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.15%
CAS 1129403-56-0
Solubility Information DMSO : ≥ 30 mg/mL (55.59 mM)
Synonym BBI503
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C31H33N5O2S
Formula Weight 539.69
14

Acrizanib, MedChemExpress

MedChemExpress Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 445.4
Color White
Physical Form Solid
Chemical Name or Material Acrizanib
Grade Research
SMILES O=C(N1C2=CC=C(OC3=NC=NC(CNC)=C3)C=C2C=C1)NC4=NN(C)C(C(F)(F)F)=C4
Percent Purity 98.23%
CAS 1229453-99-9
Solubility Information DMSO : 41.67 mg/mL (93.56 mM; Need ultrasonic)
Synonym LHA510
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C20H18F3N7O2
Formula Weight 445.4
15

c-Fms-IN-3, MedChemExpress

MedChemExpress c-Fms-IN-3 is a novel c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 406.52
Color Off-White
Physical Form Solid
Chemical Name or Material c-Fms-IN-3
Grade Research
SMILES CN(CC1)CCN1C2=CC=C(NC(C3=CC(C#N)=CN3)=O)C(N4CCC(C)CC4)=C2
Percent Purity 99.39%
CAS 885704-21-2
Solubility Information DMSO : 25 mg/mL (61.50 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H30N6O
Formula Weight 406.52