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Antibiotics

Antibiotics are compounds and substances that kill or inhibit the growth of bacteria and are commonly used to prevent bacterial contamination in cell cultures. Our extensive range of antibiotics is available in various quantities, molecular weights, and concentrations to suit your specific requirements.

FEATURED

Gibco™ Hygromycin B (50mg/mL)

Water-soluble antibiotic purified from bacterium Streptomyces hydroscopicus. Mode of action is ideal for dual- selection experiments.

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HyClone™ Penicillin Streptomycin 100X Solution

Broad spectrum bacteriostatic

Active against Gram-negative and Gram-positive organisms. Can be used as an antibacterial or an antimycobacterial.

 

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Ampicillin Sodium Salt (Crystalline Powder), Fisher BioReagents™

For selection of ampicillin resistance

Used for the selection of ampicillin-resistant mutated and transformed cells.

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Complete Your Order - Great Deals

BD BBL™ Sensi-Disc™ Dispenser for use with Sensi-Disc™ Antibiotic Susceptibility Test Discs

Six-place, self-tamping dispenser for BD BBL™ Sensi-Disc™ antibiotic susceptibility test discs. Supplied with a storage canister and a reusable indicator desiccant container.

Petri Dishes

Our range of Petri dishes are specifically designed for microbiology or cell culture use. Available in borosilicate glass or clear plastic, either round or square, our dishes come in a variety of sizes and may be ordered either disposable or reusable according to your needs.

Thermo Scientific™ 8mm Assembled Amber Autosampler Vial Kits

Save time and reduce the risk of contamination using this convenient kit. It includes 100 amber vials pre-assembled with 100 screw thread caps and septa.

FAQ

Antibiotics can be classified into several types based on their chemical structure and mechanism of action. Here are seven major types:

  1. Penicillins: These antibiotics, such as amoxicillin and penicillin, work by interfering with the synthesis of bacterial cell walls
  2. Cephalosporins: Similar to penicillins, cephalosporins (e.g., cephalexin, ceftriaxone) also disrupt bacterial cell wall synthesis but have a broader spectrum of activity
  3. Macrolides: This class, including azithromycin and erythromycin, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
  4. Fluoroquinolones: Antibiotics like ciprofloxacin and levofloxacin act by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication
  5. Tetracyclines: Tetracycline and doxycycline inhibit protein synthesis by binding to the 30S ribosomal subunit, preventing the addition of amino acids to the growing peptide chain
  6. Aminoglycosides: These antibiotics, such as gentamicin and amikacin, also inhibit protein synthesis by binding to the 30S ribosomal subunit but often require oxygen-dependent transport into the bacterial cell
  7. Sulfonamides: Sulfamethoxazole, often combined with trimethoprim (as in co-trimoxazole), inhibits folic acid synthesis, which is necessary for bacterial DNA and RNA synthesis

These categories encompass a wide range of antibiotics used to treat various bacterial infections.

Some common antibiotics for gram-positive and gram-negative bacteria are:

Gram-Positive Bacteria

  • Penicillins: Penicillin G, Amoxicillin
  • Cephalosporins: Cephalexin
  • Macrolides: Erythromycin, Azithromycin
  • Glycopeptides: Vancomycin
  • Lincosamides: Clindamycin

Gram-Negative Bacteria

  • Aminoglycosides: Gentamicin, Amikacin
  • Fluoroquinolones: Ciprofloxacin, Levofloxacin
  • Cephalosporins: Ceftriaxone, Ceftazidime
  • Carbapenems: Imipenem, Meropenem
  • Monobactams: Aztreonam

Broad-Spectrum Antibiotics

  • Tetracyclines: Doxycycline
  • Sulfonamides: Trimethoprim-sulfamethoxazole
  • Extended-Spectrum Penicillins: Piperacillin

These antibiotics are chosen based on the type of bacteria, infection site, and resistance patterns.

Antibiotics can be classified into several types based on their chemical structure and mechanism of action. Here are seven major types:

  1. Penicillins: These antibiotics, such as amoxicillin and penicillin, work by interfering with the synthesis of bacterial cell walls
  2. Cephalosporins: Similar to penicillins, cephalosporins (e.g., cephalexin, ceftriaxone) also disrupt bacterial cell wall synthesis but have a broader spectrum of activity
  3. Macrolides: This class, including azithromycin and erythromycin, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
  4. Fluoroquinolones: Antibiotics like ciprofloxacin and levofloxacin act by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication
  5. Tetracyclines: Tetracycline and doxycycline inhibit protein synthesis by binding to the 30S ribosomal subunit, preventing the addition of amino acids to the growing peptide chain
  6. Aminoglycosides: These antibiotics, such as gentamicin and amikacin, also inhibit protein synthesis by binding to the 30S ribosomal subunit but often require oxygen-dependent transport into the bacterial cell
  7. Sulfonamides: Sulfamethoxazole, often combined with trimethoprim (as in co-trimoxazole), inhibits folic acid synthesis, which is necessary for bacterial DNA and RNA synthesis

These categories encompass a wide range of antibiotics used to treat various bacterial infections.

Resources and Related Information

The Fight Against Antimicrobial Resistance: An Urgent Global Challenge

Learn more about how multidrug-resistant bacteria, resistant to most conventional antibiotics, pose a growing threat to global health.

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Antibiotics for Cell Culture

Find information on antibiotics for mammalian cell culture, plant cell culture and DNA, RNA and protein modification.

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Media Mastery for Cell Culture

Find information on everything related to cell culture.

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