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Tocris Bioscience™ LDN 193189 dihydrochloride
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Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs
| Target | BMP and Other Activin Receptor Inhibitors |
|---|---|
| CAS | 1435934-00-1 |
| Product Type | Bioactive Small Molecule |
| Color | Orange |
| Purity | 98% |
| Physical Form | Solid |
| Chemical Name or Material | 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride |
| Recommended Storage | Store at -20°C |
| Synonym | 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride |
| Molecular Formula | C25H22N60.2 HCl |
| Formula Weight | 479.4 |
Tocris Bioscience™ SB 431542
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| CAS | 301836-41-9 |
|---|---|
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C22H16N4O3 |
| Formula Weight | 384.39 |
Tocris Bioscience™ A 83-01
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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A 83-01 synthesized to Ancillary Material Grade
Tocris Bioscience™ DZNep HCl
Greener Choice Product
This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
Tocris Bioscience™ Adaptaquin
Greener Choice Product
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HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 385786-48-1 |
| Purity | >97% |
| Chemical Name or Material | 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H16ClN3O2 |
| Formula Weight | 377.82 |
Tocris Bioscience™ T3 CLK
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Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
| Target | Cdc2-like Kinase Inhibitors |
|---|---|
| CAS | 2109805-56-1 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H30N6O2 |
Tocris Bioscience™ LDN 193189 in solution
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
| Target | Other Oxidase/Oxygenase Compounds |
|---|---|
| CAS | 2280037-51-4 |
| Purity | 0.98 |
| Chemical Name or Material | 4-Amino-1-[1,1'-biphenyl]-3-yl-5-chloro-2(1H)-pyrimidinone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H12ClN3O |
Tocris Bioscience™ Staurosporine
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Staurosporine synthesized to Ancillary Material Grade
Tocris Bioscience™ Nicotinamide Riboside
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NAD+ precursor; substrate for nicotinamide riboside kinases
Tocris Bioscience™ DAPT
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DAPT synthesized to Ancillary Material Grade
Tocris Bioscience™ Nicotinamide
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Nicotinamide synthesized to Ancillary Material Grade
Tocris Bioscience™ endo-IWR 1
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endo-IWR 1 synthesized to Ancillary Material Grade
Tocris Bioscience™ T3
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T3 synthesized to Ancillary Material Grade
| Target | Compounds for Stem Cell Differentiation |
|---|---|
| CAS | 6893-02-03. |
| Purity | 0.98 |
| Chemical Name or Material | O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine |
| Molecular Formula | C15H12I3NO4 |
Tocris Bioscience™ BDY FL Staurosporine
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays