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  5. Tocris Bioscience™ Adaptaquin

Tocris Bioscience™ Adaptaquin
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Product Code. 18727516
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18727516 50 mg 50mg
18716516 10 mg 10mg
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Product Code. 18727516

Brand: Tocris Bioscience™ 5953/50

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Description

HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant

Adaptaquin is a HIF-prolyl hydroxylase-2 (PHD2) inhibitor. Blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
CAS 385786-48-1
Quantity 50 mg
Target Hydrolase Inhibitors
Molecular Formula C21H16ClN3O2
Formula Weight 377.82
Purity >97%
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