Phenoxyacetic acid derivatives

1 – 9 of 9 results

Taprenepag, MedChemExpress

MedChemExpress Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively. Taprenepag shows selectivity for EP2 over other EP receptors (IC50s>3200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	478.52
Color	White
Physical Form	Solid
Chemical Name or Material	Taprenepag
Grade	Research
SMILES	O=S(C1=CN=CC=C1)(N(CC2=CC(OCC(O)=O)=CC=C2)CC3=CC=C(N4C=CC=N4)C=C3)=O
Percent Purity	99.54%
CAS	752187-80-7
Solubility Information	DMSO : ≥ 100 mg/mL (208.98 mM)
Health Hazard 1	H303∣H320
Synonym	CP-544326
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₂N₄O₅S
Formula Weight	478.52

GPR120 modulator 1, MedChemExpress

MedChemExpress GPR120 modulator 1 is a G protein coupled receptor 120 (GPR120) modulator extracted from patent US8394841B2, compound example F1. GPR120 modulator 1 can be used for the research of diseases associated with abnormal or deregulated GPR120, such as diabetes.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	389.85
Color	White
Physical Form	Solid
Chemical Name or Material	GPR120 modulator 1
Grade	Research
SMILES	O=C(O)COC1=CC=C(OCC2=NC(C3=CC=CC=C3Cl)=CS2)C=C1C
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	98.56%
CAS	1050506-75-6
Solubility Information	DMSO : ≥ 100 mg/mL (256.51 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₆ClNO₄S
Formula Weight	389.85

GW 501516, MedChemExpress

MedChemExpress GW 501516 (GW 1516) is a PPARδ agonist with an EC50 of 1.1 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	453.5
Color	White
Physical Form	Solid
Chemical Name or Material	GW 501516
Grade	Research
SMILES	OC(COC1=CC=C(C=C1C)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	97.24%
CAS	317318-70-0
Solubility Information	DMSO : ≥ 100 mg/mL (220.51 mM)
Synonym	GW 1516 GSK-516
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₁₈F₃NO₃S₂
Formula Weight	453.5

BMS-309403, MedChemExpress

MedChemExpress BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	474.55
Color	White
Physical Form	Powder
Chemical Name or Material	BMS-309403
Grade	Research
SMILES	O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.0%
CAS	300657-03-8
Solubility Information	DMSO : 100 mg/mL (210.73 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₁H₂₆N₂O₃
Formula Weight	474.55

AP1867, MedChemExpress

MedChemExpress AP1867 is a synthetic FKBP12F36V-directed ligand.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	693.78
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	AP1867
Grade	Research
SMILES	COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)C4=CC=CC(OCC(O)=O)=C4)C=C1OC
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.29%
CAS	195514-23-9
Solubility Information	DMSO : ≥ 125 mg/mL (180.17 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₈H₄₇NO₁₁
Formula Weight	693.78

SAFit1, MedChemExpress

MedChemExpress SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	747.87
Color	White
Physical Form	Solid
Chemical Name or Material	SAFit1
Grade	Research
SMILES	O=C(N1[C@@H](CCCC1)C(O[C@@H](C2=CC(OCC(O)=O)=CC=C2)CCC3=CC(OC)=C(OC)C=C3)=O)[C@@H](C4CCCCC4)C5=CC(OC)=C(OC)C(OC)=C5
For Use With (Application)	Neuroscience-Neurodegeneration
Percent Purity	99.0%
CAS	1643125-32-9
Solubility Information	DMSO : ≥ 300 mg/mL (401.14 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₄₂H₅₃NO₁₁
Formula Weight	747.87

IMR-1A, MedChemExpress

MedChemExpress IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	325.36
Color	Yellow
Physical Form	Solid
Chemical Name or Material	IMR-1A
Grade	Research
SMILES	O=C(O)COC1=CC=C(/C=C(SC(N2)=S)\C2=O)C=C1OC
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.23%
CAS	331862-41-0
Solubility Information	DMSO : 2 mg/mL (6.15 mM; Need ultrasonic) ∣H2O : 1 mg/mL (3.07 mM; ultrasonic and warming and heat to 80°C)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₃H₁₁NO₅S₂
Formula Weight	325.36

PROTAC BRD9-binding moiety 1 hydrochloride, MedChemExpress

MedChemExpress PROTAC BRD9-binding moiety 1 hydrochloride is a compound that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	556.05
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	PROTAC BRD9-binding moiety 1 hydrochloride
Grade	Research
SMILES	O=C(O)COC1=CC=C(C2=CN(C)C(C3=C2SC(C(NC(CC4)CCS4(=O)=O)=N)=C3)=O)C=C1OC.Cl
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	97.07%
Solubility Information	DMSO : 20.83 mg/mL (37.46 mM; Need ultrasonic) ∣H2O : 2.5 mg/mL (4.50 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₃H₂₆ClN₃O₇S₂
Formula Weight	556.05

Sofalcone, MedChemExpress

MedChemExpress Sofalcone, a gastric antiulcer agent, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	450.52
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	Sofalcone
Grade	Research
SMILES	O=C(O)COC1=CC(OC/C=C(C)/C)=CC=C1C(/C=C/C2=CC=C(OC/C=C(C)/C)C=C2)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.12%
CAS	64506-49-6
Solubility Information	DMSO : ≥ 100 mg/mL (221.97 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₃₀O₆
Formula Weight	450.52

Phenoxyacetic acid derivatives

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