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Filtered Search Results
Eribulin mesylate, MedChemExpress
MedChemExpress Eribulin mesylate (E7389 mesylate) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin mesylate inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules.
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Decitabine, MedChemExpress
MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.
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| Molecular Weight (g/mol) | 228.21 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Decitabine |
| Grade | Research |
| SMILES | O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 95.0% |
| CAS | 2353-33-5 |
| Solubility Information | DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic) |
| Health Hazard 1 | H302∣H315∣H319∣H335 |
| Synonym | 5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716 |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C8H12N4O4 |
| Formula Weight | 228.21 |
Fiacitabine, MedChemExpress
MedChemExpress Fiacitabine(NSC 382097; FIAC; FOAC) is a selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively.
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| Molecular Weight (g/mol) | 371.1 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | Fiacitabine |
| Grade | Research |
| SMILES | O=C(N=C1N)N([C@@H]([C@H]([C@@H]2O)F)O[C@@H]2CO)C=C1I |
| For Use With (Application) | COVID-19-anti-virus |
| Percent Purity | 98.83% |
| CAS | 69123-90-6 |
| Solubility Information | DMSO : ≥ 37 mg/mL (99.70 mM) |
| Synonym | NSC 382097 FIAC FOAC |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C9H11FIN3O4 |
| Formula Weight | 371.1 |
M3258, MedChemExpress
MedChemExpress M3258 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor.
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| Molecular Weight (g/mol) | 329.16 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | M3258 |
| Grade | Research |
| SMILES | O=C(N[C@@H](CC1=COC2=C1C=CC=C2)B(O)O)[C@H]3[C@@H]4CC[C@@H](O4)C3 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.0% |
| CAS | 2285330-15-4 |
| Solubility Information | DMSO : 250 mg/mL (759.51 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C17H20BNO5 |
| Formula Weight | 329.16 |
Drospirenone, MedChemExpress
MedChemExpress Drospirenone(Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone.
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| Molecular Weight (g/mol) | 366.49 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Drospirenone |
| Grade | Research |
| SMILES | C[C@@]12[C@](OC3=O)(CC3)[C@@H](C4)[C@@H]4[C@@]1([H])[C@@]([C@@H]5[C@H]6C5)([H])[C@]([C@](C6=CC7=O)(CC7)C)([H])CC2 |
| Percent Purity | 98.0% |
| CAS | 67392-87-4 |
| Solubility Information | DMSO : 50 mg/mL (136.43 mM; Need ultrasonic) |
| Health Hazard 1 | H360 |
| Synonym | Dihydrospirorenone |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H30O3 |
| Formula Weight | 366.49 |
Alfuzosin, MedChemExpress
MedChemExpress Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH).
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| Molecular Weight (g/mol) | 389.45 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Alfuzosin |
| Grade | Research |
| SMILES | O=C(C1OCCC1)NCCCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)C |
| Percent Purity | 99.67% |
| CAS | 81403-80-7 |
| Solubility Information | DMSO : ≥ 50 mg/mL (128.39 mM) |
| Synonym | SL 77499 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H27N5O4 |
| Formula Weight | 389.45 |
Tegafur, MedChemExpress
MedChemExpress Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil.
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| Molecular Weight (g/mol) | 200.17 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Tegafur |
| Grade | Research |
| SMILES | O=C1NC(C(F)=CN1C2OCCC2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.74% |
| CAS | 17902-23-7 |
| Solubility Information | DMSO : ≥ 48 mg/mL (239.80 mM) |
| Health Hazard 1 | H301∣H311∣H331 |
| Synonym | FT 207 NSC 148958 |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C8H9FN2O3 |
| Formula Weight | 200.17 |
Bilobalide, MedChemExpress
MedChemExpress Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons.
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| Molecular Weight (g/mol) | 326.3 |
|---|---|
| Color | White |
| Physical Form | Powder |
| Chemical Name or Material | Bilobalide |
| Grade | Research |
| SMILES | O=C(O1)C[C@@]2([C@]1([H])C[C@]3(C(C)(C)C)O)[C@@]34[C@](OC([C@@H]4O)=O)([H])OC2=O |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 98.0% |
| CAS | 33570-04-6 |
| Solubility Information | DMSO : ≥ 100 mg/mL (306.47 mM) |
| Synonym | (-)-Bilobalide |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H18O8 |
| Formula Weight | 326.3 |
Magnolin, MedChemExpress
MedChemExpress Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 416.46 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Magnolin |
| Grade | Research |
| SMILES | COC1=C(OC)C(OC)=CC([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OC)C(OC)=C4)OC[C@@]32[H])=C1 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.85% |
| CAS | 31008-18-1 |
| Solubility Information | DMSO : 100 mg/mL (240.12 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C23H28O7 |
| Formula Weight | 416.46 |
Zylofuramine, MedChemExpress
MedChemExpress Zylofuramine is a psychomotor stimulant.
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| Molecular Weight (g/mol) | 219.32 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Zylofuramine |
| Grade | Research |
| SMILES | CCN[C@@H]([C@@]1([H])CCCO1)CC2=CC=CC=C2 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.87% |
| CAS | 3563-92-6 |
| Solubility Information | DMSO : ≥ 100 mg/mL (455.95 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C14H21NO |
| Formula Weight | 219.32 |
Dehydroascorbic acid, MedChemExpress
MedChemExpress Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.
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8-Hydroxyguanosine, MedChemExpress
MedChemExpress 8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
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3'-Azido-3'-deoxy-beta-L-uridine, MedChemExpress
MedChemExpress 3'-Azido-3'-deoxy-beta-L-uridine (Compound 25) is a nucleoside derivative.
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| Molecular Weight (g/mol) | 269.21 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | 3'-Azido-3'-deoxy-beta-L-uridine |
| Grade | Research |
| SMILES | O=C(N([C@H]1O[C@@H](CO)[C@H](N=[N+]=[N-])[C@@H]1O)C=C2)NC2=O |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.7% |
| CAS | 2095417-28-8 |
| Solubility Information | DMSO : 125 mg/mL (464.32 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C9H11N5O5 |
| Formula Weight | 269.21 |
3'-Azido-3'-deoxy-5-fluorocytidine, MedChemExpress
MedChemExpress 3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative.
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| Molecular Weight (g/mol) | 286.22 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | 3'-Azido-3'-deoxy-5-fluorocytidine |
| Grade | Research |
| SMILES | O=C1N([C@@H]2O[C@H](CO)[C@@H](N=[N+]=[N-])[C@H]2O)C=C(F)C(N)=N1 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.98% |
| CAS | 2095417-18-6 |
| Solubility Information | DMSO : 140 mg/mL (489.13 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C9H11FN6O4 |
| Formula Weight | 286.22 |