CAS RN 516-72-3
20Alpha-Hydroxy Cholesterol, TRC
CAS: 516-72-3 Molecular Formula: C27 H46 O2 Molecular Weight (g/mol): 402.65 Synonym: Cholest-5-ene-3,20-diol, (3β)-,Cholest-5-ene-3β,20-diol, (20S)- (8CI),(3β)-Cholest-5-ene-3,20-diol,(20S)-20-Hydroxycholesterol,(20S)-Hydroxycholesterol,20S-Cholest-5-ene-3β,20-diol,20α-Hydroxycholesterol,Cholest-5-ene-3β,20α-diol,20α-Hydroxy Cholesterol IUPAC Name: (3S,8S,9S,10R,13S,14S,17S)-17-[(2S)-2-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SMILES: CC(C)CCC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
20(S)-Hydroxycholesterol, MedChemExpress
MedChemExpress 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.