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20(S)-Hydroxycholesterol, MedChemExpress

Product Code. 16475088
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Product Code. 16475088 Supplier Medchem Express Supplier No. HY12316

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Description

MedChemExpress 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.

20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.

Specifications

Chemical Name or Material 20(S)-Hydroxycholesterol
CAS 516-72-3
Color White
Purity Grade Notes Research
Molecular Formula C27H46O2
Quantity 10 mg
Synonym 20α-Hydroxycholesterol
Solubility Information DMSO : 30 mg/mL (74.51 mM; ultrasonic and warming and heat to 60°C)
SMILES C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
Molecular Weight (g/mol) 402.65
Formula Weight 402.65
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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