CAS RN 405060-95-9
CAS RN 405060-95-9
IUPAC Name:
3-phenyl-N-(2,2,2-trichloro-1-{[(quinolin-8-yl)carbamothioyl]amino}ethyl)prop-2-enamide
Synonyms:
salubrinal
Molecular Weight (g/mol):
479.8
Molecular Formula:
C21H17Cl3N4OS
InChi Key:
LCOIAYJMPKXARU-UHFFFAOYNA-N
SMILES:
ClC(Cl)(Cl)C(NC(=S)NC1=C2N=CC=CC2=CC=C1)NC(=O)C=CC1=CC=CC=C1
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Thermo Scientific Chemicals Salubrinal
CAS: 405060-95-9 Molecular Formula: C21H17Cl3N4OS,C21H17Cl3N4OS Synonym: eIF-2alpha Inhibitor; SAL
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Salubrinal, MedChemExpress
MedChemExpress Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation. Salubrinal acts as a dual-specificity phosphatase 2 (Dusp2) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5.
