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CAS RN 209984-56-5

CH3ONHNOCH3HNOFF

CAS RN 209984-56-5

IUPAC Name: 2-[2-(3,5-difluorophenyl)acetamido]-N-{8-methyl-9-oxo-8-azatricyclo[9.4.0.0²,⁷]pentadeca-1(15),2,4,6,11,13-hexaen-10-yl}propanamide
Synonyms: 2-[2-(3,5-difluorophenyl)acetamido]-N-{8-methyl-9-oxo-8-azatricyclo[9.4.0.0²,⁷]pentadeca-1(15),2,4,6,11,13-hexaen-10-yl}propanamide
Molecular Weight (g/mol): 463.49
Molecular Formula: C26H23F2N3O3
InChi Key: QSHGISMANBKLQL-UHFFFAOYNA-N
SMILES: CC(NC(=O)CC1=CC(F)=CC(F)=C1)C(=O)NC1C2=CC=CC=C2C2=CC=CC=C2N(C)C1=O
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1 – 6 of 6 results
2

Tocris Bioscience™ DBZ
GREENER_CHOICE

γ-secretase inhibitor; inhibits Notch pathway

CAS 209984-56-5
Chemical Name or Material DBZ
Recommended Storage Store at -20°C
Molecular Formula C26H23F2N3O3
Formula Weight 463.48
Assay Percent Range >98%
3

Dibenzazepine (Deshydroxy LY 411575), TRC

CAS: 209984-56-5 Molecular Formula: C26 H23 F2 N3 O3 Molecular Weight (g/mol): 463.48 Synonym: Dibenzazepine IUPAC Name: (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide SMILES: C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]2C(=O)N(C)c3ccccc3c4ccccc24

CAS 209984-56-5
Molecular Weight (g/mol) 463.48
SMILES C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]2C(=O)N(C)c3ccccc3c4ccccc24
Synonym Dibenzazepine
IUPAC Name (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
Molecular Formula C26 H23 F2 N3 O3
4

YO-01027, MedChemExpress

MedChemExpress YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 463.48
Color White
Physical Form Powder
Chemical Name or Material YO-01027
Grade Research
SMILES O=C(N[C@@H](C)C(N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C)C1=O)=O)CC4=CC(F)=CC(F)=C4
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 209984-56-5
Solubility Information DMSO : 50 mg/mL (107.88 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1 H302∣H315∣H319∣H335
Synonym Dibenzazepine DBZ
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C26H23F2N3O3
Formula Weight 463.48
5

STEMCELL Technologies DBZ

Notch pathway inhibitor; Inhibits γ-secretase

ENCOMPASS_PREFERRED
6

Tocris Bioscience™ DBZ
GREENER_CHOICE

DBZ synthesized to Ancillary Material Grade