Tocris Bioscience™ Z-Guggulsterone

Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)

Produktcode	Marke	Quantity
18095222	Tocris Bioscience™ 3570/50	50 mg
18095212	Tocris Bioscience™ 3570/10	10 mg

Beschreibung

Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).

Spezifikation

• Purity: >98%
• Product Type: Z-Guggulsterone
• Molecular Weight (g/mol): 312.45
• Inhibitors: Z-Guggulsterone

For Research Use Only