Tocris Bioscience™ Z-Guggulsterone

Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)

Brand:  Tocris Bioscience™ 3570/50

Product Code. 18095222

Description

Z-Guggulsterone is a broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).

Specifications

• Purity: >98%
• Product Type: Z-Guggulsterone
• Inhibitors: Z-Guggulsterone

• Quantity: 50 mg
• Molecular Weight (g/mol): 312.45

For Research Use Only