Invitrogen™ Thyroglobulin Monoclonal Antibody (TG8.1), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17860416	Invitrogen™ MA5-46142	100 μg
11558882	Invitrogen™ MA110595	500 μg
17850466	Invitrogen™ MA5-45993	1 mg

Description

MA1-10595 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10595 has been successfully used in ELISA applications. The MA1-10595 immunogen is purified human Thyroglobulin.

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Specifications

• Antigen: Thyroglobulin
• Concentration: 1.2 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with no preservative; pH 7.4
• Gene Alias: AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor
• Gene Symbols: TG
• Isotype: IgM
• Purification Method: Protein A
• Product Type: Antibody

• Clone: TG8.1
• Applications: ELISA
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P01266
• Gene ID (Entrez): 7038
• Immunogen: Purified human Thyroglobulin.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: TG