Invitrogen™ Thyroglobulin Monoclonal Antibody (TG8.1), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA5-46142

Product Code. 17860416

Description

MA1-10595 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10595 has been successfully used in ELISA applications. The MA1-10595 immunogen is purified human Thyroglobulin.

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Specifications

• Antigen: Thyroglobulin
• Classification: Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P01266
• Gene Symbols: TG
• Immunogen: Purified human Thyroglobulin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: ELISA
• Clone: TG8.1
• Conjugate: Unconjugated
• Gene: TG
• Gene Alias: AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7038
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid