missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Survivin Ab-6, Rabbit Polyclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ Survivin Ab-6, Rabbit Polyclonal Antibody.
£133.62 - £617.10
Specifications
| Antigen | Survivin Ab-6 |
|---|---|
| Concentration | 1mg/mL |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Formulation | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Formulation | Price | Quantity & Availability | ||||
|
12603087
|
Epredia
RB-1629-P0 |
100 μL | Purified with BSA and Azide | ||||||
|
12613087
|
Epredia
RB-1629-P1 |
500 μL | Purified with BSA and Azide | ||||||
|
12623087
|
Epredia
RB-1629-P1ABX |
500 μL | Purified w/o BSA and Azide | ||||||
|
12693077
|
Epredia
RB-1629-P |
1 mL | Purified with BSA and Azide | ||||||
|
12633087
|
Epredia
RB-1629-PABX |
1 mL | Purified w/o BSA and Azide | ||||||
Description
Survivin, a new inhibitor of apoptosis (IAP) protein, is expressed in the G2/M phase of the cell cycle in a cycle-regulated manner. At the beginning of mitosis, survivin associates with microtubules of the mitotic spindle in a specific and saturable reaction that is regulated by microtubule dynamics. Disruption of survivin-microtubule interactions results in loss of survivin's anti-apoptosis function and increased caspase-3 activity, a mechanism involved in cell death, during mitosis. It indicates that survivin may counteract a default induction of apoptosis in G2/M phase. The overexpression of survivin in cancer may overcome this apoptotic checkpoint and favour aberrant progression of transformed cells through mitosis.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human and Mouse. Others not tested.
Epitope: C-terminal
Immunogen: A synthetic peptide derived from the C-terminus of survivin
Molecular Weight: 16.5kDa
Positive Control: Stomach
Cellular Localization: Cytoplasmic and Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Note:
USA: RUO; Int'l: RUO
Specifications
| Survivin Ab-6 | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Apoptosis | |
| A synthetic peptide derived from the C-terminus of survivin | |
| Primary |
| 1mg/mL | |
| Polyclonal | |
| Concentrated | |
| RUO | |
| Human | |
| IgG |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title