SQLE Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16830304	Proteintech 12544-1-AP-20UL	20 μL
16820304	Proteintech 12544-1-AP-150UL	150 μL

Description

SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64kd.

Specifications

• Antigen: SQLE
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Immunofluorescence, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Rat, Mouse
• Gene Accession No.: P52019, P52020, Q14534
• Gene ID (Entrez): 20775, 29230, 6713
• Immunogen: SQLE Fusion Protein Ag3266
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SQLE

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: ERG1, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase
• Gene Symbols: SQLE
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody