SFTPC Rabbit anti-Human, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16817383	Proteintech 10774-1-AP-20UL	20 μL
16807383	Proteintech 10774-1-AP-150UL	150 μL

Description

This antibody (Product No. 10774-1-AP) is a rabbit polyclonal antibody raised with the full-length SFTPC of human origin.

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Specifications

• Antigen: SFTPC
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Human
• Gene Accession No.: P11685, P11686
• Gene ID (Entrez): 50683, 6440
• Immunogen: SFTPC Fusion Protein Ag1159
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SFTPC

• Concentration: 0.32 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: PSP C, SFTP2, SFTPC, SMDP2, SP C, SP5, surfactant protein C
• Gene Symbols: SFTPC
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody