SFTPC Rabbit anti-Human, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10774-1-AP-20UL

Product Code. 16817383

Description

This antibody (Product No. 10774-1-AP) is a rabbit polyclonal antibody raised with the full-length SFTPC of human origin.

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Specifications

• Antigen: SFTPC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SFTPC
• Gene Alias: PSP C, SFTP2, SFTPC, SMDP2, SP C, SP5, surfactant protein C
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50683, 6440
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Concentration: 0.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P11685, P11686
• Gene Symbols: SFTPC
• Immunogen: SFTPC Fusion Protein Ag1159
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Human
• Product Type: Antibody
• Isotype: IgG