Thermo Scientific™ Pierce™ DSS Crosslinker

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Brand:  Thermo Scientific™ 21655

Product Code. 10138353

Description

Highlights:

• Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
• “Fix” protein interactions to allow identification of weak or transient protein interactions
• Protein crosslinking to create bioconjugates via single-step reactions
• Crosslink oriented antibodies to Protein A or G agarose
• Immobilize proteins onto amine-coated surfaces

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Specifications

• Spacer Arm Length: 11.4Å
• Cleavable: No
• Sufficient For: 136mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
• Membrane Permeable: Yes
• PEGylated: No
• Quantity: 50mg

• Formulation: Disuccinimidyl suberate; powder solid
• Molecular Weight: 368.34
• Description: Pierce DSS
• Chemical Reactivity: Amine-to-Amine
• Water Soluble: No