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Crosslinking, Labeling and Protein Modification

A variety of reagents used to modify proteins for identification, analysis, research, and other applications.
Protein Labeling Reagents (904)
Protein and Antibody Labeling Kits (264)
Protein Modification Reagents (251)
Crosslinking Reagents (135)
Tandem Mass Tag Reagents (48)

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1 – 15 of 962 results
1

Thermo Scientific™ EZ-Link™ NHS-PEG4-Biotin

Thermo Scientific™ EZ-Link™ NHS-PEG4-Biotin is a pegylated, water-soluble reagent for simple and efficient biotin labeling of antibodies, proteins and other primary amine-containing macromolecules.

EDGE
Cell Permeability Cell-Impermeant
Content And Storage Store at -20°C.
Product Type NHS-PEG4-Biotin
Label or Dye Biotin
Solubility DMF (Dimethylformamide),DMSO (Dimethylsulfoxide),Water
Chemical Reactivity Amine
Product Line EZ-Link
2
Promotions Available

Invitrogen™ Alexa Fluor™ 647 C2 Maleimide

Alexa Fluor™ 647 is a bright, far-red fluorescent dye with excitation ideally suited for the 594 nm or 633 nm laser lines.

3

Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

EDGE
Molecular Weight (g/mol) 217.13
Solubility Water
PEGylated No
4
Promotions Available

Thermo Scientific™ Trypsin, TPCK Treated

Thermo Scientific Pierce TPCK Trypsin is a serine endoprotease that is applicable to amino acid analysis and protein sequencing, mapping and structural studies; the immobilized form allows sample separation after treatment.

EDGE
5

Thermo Scientific™ Pierce™ EDC, No-Weigh™ Format

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

EDGE
Shipping Condition Wet Ice
Content And Storage Upon receipt store desiccated at -20°C.
Description EDC
Cleavable No
Water Soluble Yes
Form Powder
Molecular Weight (g/mol) 191.7
Solubility Water
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Carboxyl
Cell Permeability No
Format Standard, Single-use, Premium-grade
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Carbodiimide
Spacer Arm Length 0.0 Å
PEGylated No
6

Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at -20°C.
Description Sulfo-SMCC
Cleavable No
Water Soluble Yes
Molecular Weight (g/mol) 436.37
Solubility Water
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Sulfhydryl
Cell Permeability No
Format Standard, Single-use, Premium-grade
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Maleimide, Sulfo-NHS Ester
Spacer Arm Length 8.3 Å
PEGylated No
7

Thermo Scientific™ Pierce™ Sulfo-SANPAH, No-Weigh™ Format

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store at -20°C protected from light and moisture.
Cleavable By Thiols
Water Soluble Yes
Form Powder
Molecular Weight (g/mol) 492.4
Solubility Water
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Nonselective
Cell Permeability No
Format Standard, Single-use
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Spacer Arm Length 18.2 Å
PEGylated No
8

Thermo Scientific™ Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Optimize applications where product integrity and risk minimization are paramount with this high-quality formulation of carbodiimide crosslinker.

EDGE
Content And Storage Upon receipt store desiccated at -20°C.
Cleavable No
Water Soluble Yes
Molecular Weight (g/mol) 191.7
Solubility Water
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Carboxyl
Cell Permeability No
Format Standard, Single-use, Premium-grade
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Carbodiimide
Spacer Arm Length 0.0 Å
Product Line Pierce
PEGylated No
9

Invitrogen™ Alexa Fluor™ 568 NHS Ester (Succinimidyl Ester)

Alexa Fluor™ 568 is a bright orange dye. Used for stable signal generation in imaging and flow cytometry, Alexa Fluor™ 568 dye is water soluble and pH-insensitive from pH 4 to pH 10.

EDGE
Shipping Condition Room Temperature
Content And Storage Store in freezer (-5 to -30°C) and protect from light.
Product Type Dye
Label or Dye Alexa Fluor™ 568
Reactive Moiety Active Ester, Succinimidyl Ester
Emission 602 nm
Excitation 578 nm
Label Type Alexa Fluor
Chemical Reactivity Amine
Product Line Alexa Fluor
10

Thermo Scientific™ Pierce™ DSG, No-Weigh™ Format

EDGE
Cleavable No
Water Soluble No
Form Powder
Molecular Weight (g/mol) 326.26
Solubility DMF, DMSO
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Cell Permeability Yes
Format Standard, Single-use
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety NHS Ester
Spacer Arm Length 7.7 Å
PEGylated No
11
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Thermo Scientific™ BS(PEG)9

Crosslink amines to amines with these long (21.7A and 35.8A) crosslinkers composed of NHS-ester groups and 5-unit or 9-unit PEG spacer arms that enhance protein solubility.

EDGE
12
Promotions Available

Molecular Probes™ Alexa Fluor™ 488 Azide (Alexa Fluor™ 488 5-Carboxamido-(6-Azidohexanyl), Bis(Triethylammonium Salt)), 5-isomer

The green-fluorescent Alexa Fluor™ 488 azide is reactive with terminal alkynes via a copper-catalyzed click reaction.

EDGE
13

Thermo Scientific™ Pierce™ Iodoacetic Acid

Get rapid carboxymethylation of reduced cysteine residues with Thermo Scientific™ Pierce™ Iodoacetic Acid and Iodoacetamide.

EDGE
14
Promotions Available

Thermo Scientific™ NHS-Fluorescein (5/6-carboxyfluorescein succinimidyl ester), mixed isomer

Activated derivatives of green-fluorescent fluorescein dye to label antibodies, proteins and other molecules for fluorescence imaging (ex 494; em 518).

EDGE
Content And Storage Store desiccated at -20°C, protect from moisture
Product Type NHS-Fluorescein
Label or Dye FITC (Fluorescein)
Reactive Moiety Active Ester, Succinimidyl Ester, NHS Ester
Solubility DMF (Dimethylformamide)
Emission 518
Excitation 494
Label Type Classic Dyes
Chemical Reactivity Amine
Product Line Pierce
15
Promotions Available

Invitrogen™ Click-iT™ Plus OPP Alexa Fluor™ 647 Protein Synthesis Assay Kit
GREENER_CHOICE

Provides non-radioactive method for detection of protein synthesis using fluorescence microscopy or high-content imaging

EDGE