Thermo Scientific™ Pierce™ DMP Crosslinker

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

Brand: Thermo Scientific™

Manufacturer Part Number: 21666

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 1.81440kg

Product Code. 10097093

Quantity Price
1 £ 39.28 / 50mg
EU Stock 9
Add to basket

Description and Specification


Spacer Arm Length 9.2Å
Formulation Dimethyl pimelimidate-2HCl; powder solid
Cleavable No
Molecular Weight 259.17
Sufficient For 193mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
Membrane Permeable Yes
Description Pierce DMP
PEGylated No
Chemical Reactivity Amine-to-Amine
Quantity 50mg
Water Soluble Yes


  • Water-soluble
  • Rapid reaction with amines at alkaline pH values (pH 8-10)
  • Amidine bond retains net charge character of protein
  • Reversible at high pH values
  • Reactive groups: imidoester (homobifunctional)
  • Reactive toward: amino groups


Technical documents