Thermo Scientific™ Pierce™ BS3 (Sulfo-DSS) Crosslinker

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Overview
Brand: Thermo Scientific™

Manufacturer Part Number: 21580

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 1.81440kg



Product Code. 10249963

Quantity Price
1 £ 133.0 / 50mg
EU Stock 52
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Description and Specification

Specification

Spacer Arm Length 11.4Å
Formulation Bis(sulfosuccinimidyl) suberate; powder solid
Cleavable No
Molecular Weight 572.43
Sufficient For 87mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
Membrane Permeable No
Description Pierce BS3 (Sulfo-DSS)
Chemical Reactivity Amine-to-Amine
PEGylated No
Quantity 50mg
Water Soluble Yes

Highlights:

  • Crosslink cell-surface proteins before cell lysis and immunoprecipitation
  • Identify receptor-ligand interactions by chemical crosslinking
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Identify near-neighbor protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Immobilize proteins onto amine-coated surfaces

Documentation

Technical documents