Thermo Scientific™ Pierce™ BS3 (Sulfo-DSS) Crosslinker

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Overview
Brand: Thermo Scientific™

Manufacturer Part Number: 21586

1 GR BS3

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 0.00100kg



Product Code. 10075843

Quantity Price
1 £ 1026.0 / 1g
Estimated Shipment date
from Supplier 02-01-2017
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Description and Specification

Specification

Chemical Reactivity Amine-to-Amine
Cleavable No
Description Pierce BS3
Formulation Bis(sulfosuccinimidyl) suberate; powder solid
Membrane Permeable No
Molecular Weight 572.43
PEGylated No
Quantity 1g
Sufficient For 1747mL of typical 1X (1mM) reaction solution, or approx. 500 uses at 2mg reagent per use
Spacer Arm Length 11.4Å
Water Soluble Yes

Highlights:

  • Crosslink cell-surface proteins before cell lysis and immunoprecipitation
  • Identify receptor-ligand interactions by chemical crosslinking
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Identify near-neighbor protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Immobilize proteins onto amine-coated surfaces

Documentation

Technical documents