p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results with the Epredia™ p21^WAF1 Ab-11, Mouse Monoclonal Antibody.

Product Code	Brand	Conjugate	Concentration	Quantity
12662547	Epredia MS-891-P0	Unconjugated	200μg/mL	100 μL
12682547	Epredia MS-891-PABX	Unconjugated	1mg/mL	200 μL
12612547	Epredia MS-891-B0	Biotin	200μg/mL	100 μL
12672547	Epredia MS-891-P1	Unconjugated	200μg/mL	500 μL
12652547	Epredia MS-891-P	Unconjugated	200μg/mL	1 mL
12692547	Epredia MS-891-P1ABX	Unconjugated	1mg/mL	100 μL
12632547	Epredia MS-891-B1	Biotin	200μg/mL	500 μL

Description

p21^WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21^WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21^WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: CP74

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1-80

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Raji, PC12 cells

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Native verified)
• Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: p21superscriptWAF1superscript Ab-11
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Form: Concentrated
• Regulatory Status: RUO
• Target Species: Human, Rat
• Isotype: IgG2b

• Clone: CP74
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Cycle
• Immunogen: Full length human recombinant p21 protein
• Primary or Secondary: Primary