Invitrogen™ FRS2 Recombinant Rabbit Monoclonal Antibody (1K7X4)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30282419	Invitrogen™ MA558041	20 μL
30282417	Invitrogen™ MA558042	100 μL

Description

Immunogen sequence: EEQVHTYVNT TGVQEERKNR TSVHVPLEAR VSNAESSTPK EEPSSIEDRD PQILLEPEGV KFVLGPTPVQ KQLMEKEKLE QLGRDQVSGS GANNTEWDTG.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt]

Specifications

• Antigen: FRS2
• Concentration: 1.27 mg/mL
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q8C180, Q8WU20
• Gene ID (Entrez): 10818, 314850, 327826
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 190-289 of human FRS2 (NP_006645.3).
• Product Type: Antibody

• Clone: 1K7X4
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: FRS2
• Gene Alias: 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
• Gene Symbols: FRS2
• Primary or Secondary: Primary
• Purification Method: Protein A