Invitrogen™ FRS2 Recombinant Rabbit Monoclonal Antibody (1K7X4)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA558042

Product Code. 30282417

Description

Immunogen sequence: EEQVHTYVNT TGVQEERKNR TSVHVPLEAR VSNAESSTPK EEPSSIEDRD PQILLEPEGV KFVLGPTPVQ KQLMEKEKLE QLGRDQVSGS GANNTEWDTG.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].

Specifications

• Antigen: FRS2
• Classification: Recombinant Monoclonal
• Concentration: 1.27 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q8C180, Q8WU20
• Gene Symbols: FRS2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 190-289 of human FRS2 (NP_006645.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 1K7X4
• Conjugate: Unconjugated
• Gene: FRS2
• Gene Alias: 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10818, 314850, 327826
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid