DUSP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16825575	Proteintech 27327-1-AP-20UL	20 μL
16815575	Proteintech 27327-1-AP-150UL	150 μL

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predomitly expressed in hematopoietic tissues, and is localized in the nucleus.

Specifications

• Antigen: DUSP2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q05922, Q05923
• Gene ID (Entrez): 13537, 1844
• Immunogen: DUSP2 Fusion Protein Ag25380
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DUSP2

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: dual specificity phosphatase 2, DUSP2, PAC 1, PAC1
• Gene Symbols: DUSP2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody