DUSP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27327-1-AP-150UL

Product Code. 16815575

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predomitly expressed in hematopoietic tissues, and is localized in the nucleus.

Specifications

• Antigen: DUSP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DUSP2
• Gene Alias: dual specificity phosphatase 2, DUSP2, PAC 1, PAC1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13537, 1844
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q05922, Q05923
• Gene Symbols: DUSP2
• Immunogen: DUSP2 Fusion Protein Ag25380
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG