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CD45 Mouse, anti-Human, FITC, Clone: HI30, STEMCELL Technologies

Mouse Monoclonal Antibody

POA - £257.85

Specifications

Antigen CD45
Clone HI30
Applications CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Classification Monoclonal
Conjugate FITC
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17188491
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Stemcell Technologies
60018FI.1
25 Tests
£122.85
25 tests
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17178491
Encompass_Preferred
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Stemcell Technologies
60018FI
100 Tests
£257.85
100 tests
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17137631
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Stemcell Technologies
100-0466
500 Tests This item is currently unavailable or has been discontinued.
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Description

Description

  • The HI30 antibody reacts with all isoforms of CD45, a type I transmembrane glycoprotein expressed on the surface of most hematopoietic cells except mature erythrocytes, platelets, and plasma cells; expression of CD45 is lost during differentiation of these cell types
  • CD45 is a member of the protein tyrosine phosphatase family and functions in a number of immunoregulatory processes, including cell activation, growth, differentiation, and oncogenic transformation
  • The large cytoplasmic portion of CD45 contains two tyrosine phosphatase domains that are involved in modulating the function of intracellular substrates such as the Src kinases Lck and Fyn
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human T Cell Enrichment Kit (Catalog #19051), EasySep™ Human CD4+ T Cell Enrichment Kit (Catalog #19052) and EasySep™ Human CD45 Depletion Kit II (Catalog #17898; partial blocking may be observed)
Specifications

Specifications

CD45
CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
FITC
Chimpanzee, Human
Primary
HI30
Monoclonal
Mouse
IgG1 κ
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