CD45 Mouse, anti-Human, FITC, Clone: HI30, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60018FI.1

Product Code. 17188491

Description

• The HI30 antibody reacts with all isoforms of CD45, a type I transmembrane glycoprotein expressed on the surface of most hematopoietic cells except mature erythrocytes, platelets, and plasma cells; expression of CD45 is lost during differentiation of these cell types
• CD45 is a member of the protein tyrosine phosphatase family and functions in a number of immunoregulatory processes, including cell activation, growth, differentiation, and oncogenic transformation
• The large cytoplasmic portion of CD45 contains two tyrosine phosphatase domains that are involved in modulating the function of intracellular substrates such as the Src kinases Lck and Fyn
• This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human T Cell Enrichment Kit (Catalog #19051), EasySep™ Human CD4+ T Cell Enrichment Kit (Catalog #19052) and EasySep™ Human CD45 Depletion Kit II (Catalog #17898; partial blocking may be observed)

Specifications

• Antigen: CD45
• Classification: Monoclonal
• Conjugate: FITC
• Quantity: 25 Tests
• Target Species: Chimpanzee, Human
• Cell Type: Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Leukocytes, Lymphocytes, Myeloid Cells

• Applications: CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
• Clone: HI30
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG1 κ