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beta-Estradiol, 99% (dry wt.), ca 3% water, Thermo Scientific Chemicals

£29.30 - £460.00

Chemical Identifiers

CAS 50-28-2
Molecular Formula C18H24O2
Molecular Weight (g/mol) 272.388
MDL Number MFCD00003693
InChI Key VOXZDWNPVJITMN-ZBRFXRBCSA-N
Synonym estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin
PubChem CID 5757
ChEBI CHEBI:16469
IUPAC Name (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
SMILES CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
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Product Code Brand Quantity Price Quantity & Availability  
11366656
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Thermo Scientific Alfa Aesar
L03801.03
1 g
£29.30
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Thermo Scientific Alfa Aesar
L03801.06
5 g
£117.00
5g
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Thermo Scientific Alfa Aesar
L03801.14
25 g
£460.00
25g
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Description

Description

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner′s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.

Notes
Incompatible with strong oxidizing agents.
Specifications

Chemical Identifiers

50-28-2
272.388
VOXZDWNPVJITMN-ZBRFXRBCSA-N
5757
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
C18H24O2
MFCD00003693
estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin
CHEBI:16469
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O

Specifications

50-28-2
C18H24O2
1914275
estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin
VOXZDWNPVJITMN-ZBRFXRBCSA-N
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
272.388
CHEBI:16469
99%
beta-Estradiol
175°C to 178°C
MFCD00003693
14,3703
Soluble in dimethyl sulfoxide,ethanol ,water,phosphate buffer saline,dimethyl formamide,acetone,dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
+79° (c=1 in Dioxane)
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
5757
272.39
(dry wt.), ≈3% water
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Safety and Handling

Safety and Handling

GHS H Statement
H350-H360
May cause cancer.
May damage fertility or the unborn child.

P201-P202-P260-P263-P264b-P270-P271-P281-P304+P340-P308+P313-P501c

H350-H361fd-H362-H373

missing translation for 'einecsNumber' : 200-023-8

missing translation for 'rtecsNumber' : KG2975000

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only