ANLN Mouse anti-Human, Clone: 1B4A8, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16828715	Proteintech 66643-1-IG-20UL	20 μL
16818715	Proteintech 66643-1-IG-150UL	150 μL

Description

ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.

Specifications

• Antigen: ANLN
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Actin binding protein anillin, anillin, actin binding protein, ANLN, scra, Scraps
• Gene Symbols: ANLN
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1B4A8
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q9NQW6
• Gene ID (Entrez): 54443
• Immunogen: ANLN Fusion Protein Ag19294
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ANLN