CAS RN 443913-73-3
CAS RN 443913-73-3
IUPAC Name:
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
Synonyms:
vandetanib zactima C22H24BrFN4O2 vande-tanib
Molecular Weight (g/mol):
475.36
Molecular Formula:
C22H24BrFN4O2
InChi Key:
UHTHHESEBZOYNR-UHFFFAOYSA-N
SMILES:
COC1=C(OCC2CCN(C)CC2)C=C2N=CN=C(NC3=CC=C(Br)C=C3F)C2=C1
1
–
4
of
4
results
1
Thermo Scientific Chemicals Vandetanib
CAS: 443913-73-3 Molecular Formula: C22H24BrFN4O2 Molecular Weight (g/mol): 475.36 InChI Key: UHTHHESEBZOYNR-UHFFFAOYSA-N IUPAC Name: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine SMILES: COC1=C(OCC2CCN(C)CC2)C=C2N=CN=C(NC3=CC=C(Br)C=C3F)C2=C1
2
Tocris Bioscience™ Vandetanib
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
3
STEMCELL Technologies Vandetanib
Tyrosine kinase inhibitor; Inhibits VEGFR1, KDR, FLT-4, EGFR, FGFR, ABL, RET, and SRC
4
Vandetanib, MedChemExpress
MedChemExpress Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).