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  5. Tocris Bioscience™ Vandetanib

Tocris Bioscience™ Vandetanib
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Product Code. 18795836
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18795836

Brand: Tocris Bioscience™ 7497/10

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This item is not returnable. View return policy

Description

Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity

Vandetanib is a potent VEGFR-2 inhibitor (IC50 = 0.04 μM), and inhibitor of EGFR (IC50 = 0.5 μM). Vandetanib potently inhibits (IC50 = 100 nM) RET oncoprotein activity in human thyroid cancer. Vandetanib displays anti-angiogenic properties in human nasopharyngeal carcinoma in mice model. Vandetanib is orally available and effective in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
CAS 443913-73-3
Quantity 10 mg
Target VEGF Receptor Inhibitors
Molecular Formula C22H24BrFN4O2
Purity 0.98
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