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Vandetanib, MedChemExpress

Product Code. 16491546
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Product Code. 16491546

Brand: Medchem Express HY10260

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Description

MedChemExpress Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).

Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).

Specifications

Chemical Name or Material Vandetanib
CAS 443913-73-3
Color White
Purity Grade Notes Research
Molecular Formula C22H24BrFN4O2
Quantity 500 mg
Synonym ZD6474
Solubility Information DMSO : 27.5 mg/mL (57.85 mM; Need ultrasonic and warming)
SMILES FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C)=C(C=C23)OC
Molecular Weight (g/mol) 475.35
Formula Weight 475.35
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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