CAS RN 1263094-00-3
CAS RN 1263094-00-3
IUPAC Name:
7-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid sodium
Synonyms:
7-chloro-kyurenic acid sodium
Molecular Weight (g/mol):
246.6
Molecular Formula:
C10H6ClNNaO3
InChi Key:
MNYKNNXDFLKIJJ-UHFFFAOYSA-N
SMILES:
[Na].OC(=O)C1=CC(=O)C2=CC=C(Cl)C=C2N1
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7-Chlorokynurenic acid sodium salt, MedChemExpress
MedChemExpress 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.
