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  6. 7-Chlorokynurenic acid sodium salt, MedChemExpress

7-Chlorokynurenic acid sodium salt, MedChemExpress

Product Code. 16459726
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Product Code. 16459726 Supplier Medchem Express Supplier No. HY100811A

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Description

MedChemExpress 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.

7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.

Specifications

Chemical Name or Material 7-Chlorokynurenic acid sodium salt
Physical Form Solid
CAS 1263094-00-3
Color Off-White
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C10H5ClNNaO3
For Use With (Application) Neuroscience-Neurodegeneration
Synonym 7-CKA sodium salt
Solubility Information H2O : 50 mg/mL (203.59 mM; Need ultrasonic) ∣DMSO : ≥ 33.67 mg/mL (137.10 mM)
SMILES O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O[Na]
Molecular Weight (g/mol) 245.59
Formula Weight 245.59
Percent Purity 99.32%
Grade Research
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Research purposes only

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