CAS RN 1196109-52-0
CAS RN 1196109-52-0
IUPAC Name:
N-(pyridin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxamide
Synonyms:
N-(pyridin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxamide
Molecular Weight (g/mol):
456.47
Molecular Formula:
C24H23F3N4O2
InChi Key:
NBOJHRYUGLRASX-UHFFFAOYSA-N
SMILES:
FC(F)(F)C1=CN=C(OC2=CC=CC(CC3CCN(CC3)C(=O)NC3=CN=CC=C3)=C2)C=C1
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Tocris Bioscience™ PF 3845
CAS: 1196109-52-0 Molecular Formula: C24H23F3N4O2
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PF-3845, MedChemExpress
MedChemExpress PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a Ki of 0.23 μM. PF-3845 is a covalent inhibitor that carbamylates FAAH's serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition.
