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PF-3845, MedChemExpress

Product Code. 16456048
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Description

MedChemExpress PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a Ki of 0.23 μM. PF-3845 is a covalent inhibitor that carbamylates FAAH's serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition.

PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a Ki of 0.23 μM. PF-3845 is a covalent inhibitor that carbamylates FAAH's serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition.

Specifications

Chemical Name or Material PF-3845
CAS 1196109-52-0
Color White
Purity Grade Notes Research
Molecular Formula C24H23F3N4O2
Quantity 10 mg
Solubility Information DMSO : ≥ 100 mg/mL (219.08 mM)
SMILES O=C(N1CCC(CC2=CC=CC(OC3=NC=C(C=C3)C(F)(F)F)=C2)CC1)NC4=CN=CC=C4
Molecular Weight (g/mol) 456.46
Formula Weight 456.46
Percent Purity 99.8%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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