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Crosslinking Reagents

Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.
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1 – 7 of 7 results
1

Thermo Scientific™ Pierce™ Controlled Protein-Protein Crosslinking Kit

Chemically conjugate any two purified proteins (antibodies, enzymes, carriers, etc.) using sulfo-SMCC crosslinker, a complete kit with modification reagents and buffers.

2

Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

EDGE
Content And Storage Upon receipt store desiccated at 4°C.
Description DSP
Cleavable By Thiols
Water Soluble No
Form Powder
Molecular Weight (g/mol) 404.42
Solubility DMF, DMSO
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Cell Permeability Yes
Format Standard, Single-use, Premium-grade
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Reactive Moiety NHS Ester
Spacer Arm Length 12.0 Å
PEGylated No
4

Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

Molecular Weight (g/mol) 217.13
Solubility Water
PEGylated No
5

Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Cleavable No
Product Type Crosslinker
Molecular Weight (g/mol) 572.43
Solubility Water
PEGylated No
6

Thermo Scientific™ Pierce™ Premium Grade BS3

Crosslink proteins and other biomolecules in applications where product integrity and risk minimization are paramount with Thermo Scientific™ Pierce™ Premium Grade BS3, a high-quality formulation of this popular amine-reactive crosslinker.

Product Type BS3
Form Powder
Molecular Weight (g/mol) 572.43
Solubility Water
Product Line Pierce™
7

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Cleavable No
PEGylated No