Piperidines
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PNU-282987 S enantiomer free base, MedChemExpress
MedChemExpress PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.
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| Percent Purity | 99.58% |
|---|---|
| CAS | 737727-12-7 |
| Molecular Weight (g/mol) | 264.75 |
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | PNU-282987 S enantiomer free base |
| Grade | Research |
| SMILES | O=C(C1=CC=C(Cl)C=C1)N[C@H]2C3CCN(CC3)C2 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C14H17ClN2O |
| Formula Weight | 264.75 |
DOV-216,303 Free Base, MedChemExpress
MedChemExpress DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats.
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1-Benzyl-3-piperidone hydrate hydrochloride, 95%, Thermo Scientific Chemicals
CAS: 50606-58-1 Molecular Formula: C12H16ClNO Molecular Weight (g/mol): 225.72 MDL Number: MFCD00150096 InChI Key: OVWSFXNSJDMRPV-UHFFFAOYSA-N Synonym: 1-benzyl-3-piperidone hydrochloride,1-benzylpiperidin-3-one hydrochloride,1-benzyl-3-piperidinone hydrochloride,1-benzyl-3-piperidone hydrate hydrochloride,1-benzylpiperidin-3-one hcl,1-benzyl-3-piperidone hcl hydrate,3-piperidinone, 1-phenylmethyl-, hydrochloride,1-benzyl-3-piperidinone hydrate hydrochloride,n-benzyl-3-piperidone hydrochloride,pubchem7726 PubChem CID: 3084924 IUPAC Name: 1-benzylpiperidin-3-one;hydrochloride SMILES: Cl.O=C1CCCN(CC2=CC=CC=C2)C1
| PubChem CID | 3084924 |
|---|---|
| CAS | 50606-58-1 |
| Molecular Weight (g/mol) | 225.72 |
| MDL Number | MFCD00150096 |
| SMILES | Cl.O=C1CCCN(CC2=CC=CC=C2)C1 |
| Synonym | 1-benzyl-3-piperidone hydrochloride,1-benzylpiperidin-3-one hydrochloride,1-benzyl-3-piperidinone hydrochloride,1-benzyl-3-piperidone hydrate hydrochloride,1-benzylpiperidin-3-one hcl,1-benzyl-3-piperidone hcl hydrate,3-piperidinone, 1-phenylmethyl-, hydrochloride,1-benzyl-3-piperidinone hydrate hydrochloride,n-benzyl-3-piperidone hydrochloride,pubchem7726 |
| IUPAC Name | 1-benzylpiperidin-3-one;hydrochloride |
| InChI Key | OVWSFXNSJDMRPV-UHFFFAOYSA-N |
| Molecular Formula | C12H16ClNO |
Donepezil, MedChemExpress
MedChemExpress Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively.
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| Molecular Weight (g/mol) | 379.49 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Donepezil |
| Grade | Research |
| SMILES | O=C(C(C=C(OC)C(OC)=C1)=C1C2)C2CC(CC3)CCN3CC4=CC=CC=C4 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 98.0% |
| CAS | 120014-06-4 |
| Solubility Information | DMSO : 33.33 mg/mL (87.83 mM; Need ultrasonic) ∣H2O : 2 mg/mL (5.27 mM; ultrasonic and warming and heat to 80°C) |
| Health Hazard 1 | H315∣H319∣H335 |
| Synonym | E2020 free base |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light) |
| Shelf Life | 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light) |
| Molecular Formula | C24H29NO3 |
| Formula Weight | 379.49 |